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腋窝淋巴结丝虫病

Filariasis in axillary lymph node.

作者信息

Chen L S, Wong P S, Leong K N, Chow T S

机构信息

Infectious Disease Unit, Department of Medicine, Penang General Hospital, Jalan Residensi, 10990 Georgetown, Pulau Pinang, Malaysia.

出版信息

Trop Biomed. 2017 Jun 1;34(2):461-463.

Abstract

A case of adult filarial worms detected in an axillary lymph node of an asymptomatic patient. A 64 year-old Indian female underwent a mammogram and was incidentally found to have punctate microcalcifications in the upper outer quadrant of the left breast with left axillary lymphadenopathy. She has underlying hypertension and diabetes mellitus on oral medications. She has no family history of breast malignancy. Fine needle aspiration of the left axillary lymph node was suggestive of reactive lympha-denitis. Histopathological examination of excisional biopsy of left breast lump showed fibrocystic disease; no evidence of malignancy was detected whereas excisional biopsy of left axillary lymph node showed reactive lymphoid hyperplasia, featuring variably sized lymphoid follicles with intact mantle zone. No expansion of marginal zone was noted. Occasional pigment-laden macrophages were seen. One of the lymph node showed presence of calcified serpinginous tubular bodies, in keeping with non viable parasite organisms with intact outlines of the structures. There were no eosinophilic infiltrates. The possibility of filarial infestation was suspected. Histopathological sample was sent for further identification and confirmed the presence of adult filarial worm.

摘要

在一名无症状患者的腋窝淋巴结中检测到成虫丝虫病例。一名64岁的印度女性接受了乳房X光检查,偶然发现左乳外上象限有散在微钙化灶及左侧腋窝淋巴结肿大。她患有高血压和糖尿病,正在口服药物治疗。她没有乳腺癌家族史。左腋窝淋巴结细针穿刺提示反应性淋巴结炎。左乳肿块切除活检的组织病理学检查显示为纤维囊性疾病;未发现恶性证据,而左腋窝淋巴结切除活检显示反应性淋巴样增生,其特征为大小不一的淋巴滤泡,套区完整。未观察到边缘区扩大。可见散在的含色素巨噬细胞。其中一个淋巴结显示有钙化的蜿蜒管状结构,符合结构轮廓完整的无活力寄生虫生物。无嗜酸性粒细胞浸润。怀疑有丝虫感染。组织病理学样本送去进一步鉴定,证实存在成虫丝虫。

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