Hayes W P, Meyer R L
Department of Developmental and Cell Biology, University of California, Irvine 92717.
Brain Res. 1988 Feb 1;466(2):304-12. doi: 10.1016/0165-3806(88)90058-2.
Selected optic fibers were surgically deflected from one tectum onto the opposite host tectum which was denervated by eye enucleation. At 6-8 months, deflected fibers were labeled with horseradish peroxidase and the retinotopically inappropriate part of tectum was examined using electron microscopy. Numerous (labeled) optic synapses were found in the primary optic innervation layer of the 'wrong' part of tectum but they were about half the normal density. The number and density of non-optic synapses was not found to be affected. These findings indicate optic fibers compete with each other but not with non-optic fibers for synaptic sites in tectum.
选择的视神经纤维通过手术从一个顶盖转移到对侧的宿主顶盖，该宿主顶盖已通过眼球摘除术去神经支配。在6 - 8个月时，用辣根过氧化物酶标记转移的纤维，并使用电子显微镜检查顶盖视网膜拓扑结构不适当的部分。在顶盖“错误”部分的初级视神经支配层中发现了大量（标记的）视突触，但它们的密度约为正常密度的一半。未发现非视突触的数量和密度受到影响。这些发现表明，视神经纤维在顶盖中相互竞争突触位点，但不与非视神经纤维竞争。
