Bennet Louise, Wändell Per
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senior professor, allmänmedicin, sektionen för allmänmedicin och primärvård, Neurobiologi, vårdvetenskap och samhälle, Karolinska institutet.
Lakartidningen. 2021 Feb 17;118:20177.
Non-western immigrants have a higher prevalence of type 2 diabetes and earlier onset than non-immigrant Swedes. In this 10-year follow-up including all people in Sweden diagnosed with type 2 diabetes from 2006 onwards (i.e. prescribed glucose lowering medication for type 2 diabetes), the total and cause-specific mortality of first-generation immigrants with type 2 diabetes is lower than in non-immigrant Swedes. However, the higher survival rates in first generation immigrants disappear over time and second-generation immigrants rather show higher all-cause mortality rates than native Swedes. Contributing causes may be related to acculturation to the western lifestyle and gene environment interactions but remains to be further investigated.
与非移民瑞典人相比，非西方移民的2型糖尿病患病率更高且发病更早。在这项为期10年的随访研究中，纳入了自2006年起瑞典所有被诊断为2型糖尿病的患者（即开具了2型糖尿病降糖药物的患者），患有2型糖尿病的第一代移民的全因死亡率和特定病因死亡率低于非移民瑞典人。然而，第一代移民较高的生存率会随着时间推移而消失，第二代移民的全因死亡率反而高于瑞典本地人。促成这些情况的原因可能与西方生活方式的文化适应以及基因与环境的相互作用有关，但仍有待进一步研究。
