Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.
Department of Surgery, University of Minnesota, Minneapolis, MN.
Am J Transplant. 2021 Feb;21 Suppl 2:138-207. doi: 10.1111/ajt.16496.
The overall number of pancreas transplants decreased slightly, from 1027 in 2018 to 1015, in 2019, up from a nadir of 947 in 2015. However, the number of simultaneous pancreas-kidney transplants (SPKs) increased in 2019, with a corresponding drop in pancreas-after-kidney transplants (PAKs) and pancreas transplants alone (PTAs). New waitlist registrations increased to 1772 in 2019, from 1606 in 2018. This was predominately driven by SPK listings, and those with type 2 diabetes. Waiting time for SPK decreased by 2 months, to a median of 12 months in 2019, but PTA recipient mean waiting time remained substantially higher, at 24 months, in 2018. Both short- and long-term outcomes, including patient survival, kidney graft survival, and acute rejection-free graft survival, have shown consistent improvement over the last decade. Pancreas graft survival data with the uniform definition of allograft failure is being collected by the Organ Procurement and Transplant Network (OPTN) and will be included in a future report.
胰腺移植总数略有下降,从 2018 年的 1027 例降至 2019 年的 1015 例,高于 2015 年的 947 例的最低点。然而,2019 年同时进行胰腺-肾脏移植(SPK)的数量增加,相应减少了胰腺-肾脏后移植(PAK)和单独胰腺移植(PTA)的数量。新的等候名单登记人数从 2018 年的 1606 人增加到 2019 年的 1772 人。这主要是由 SPK 登记和 2 型糖尿病患者推动的。SPK 的等待时间缩短了 2 个月,2019 年中位数为 12 个月,但 PTA 受者的平均等待时间仍然高得多,为 24 个月,2018 年为 24 个月。过去十年,包括患者存活率、肾脏移植物存活率和无急性排斥反应的移植物存活率在内的短期和长期结果均显示出持续改善。器官获取和移植网络(OPTN)正在收集具有同种异体移植失败统一定义的胰腺移植物生存数据,并将在未来的报告中包括这些数据。