Ann Ital Chir. 2021 Jan 20;10:S2239253X21035106.
Metastasis of breast cancer to the uterus is quite rare. The majority of reported cases have evolved from previously known invasive ductal and lobular carcinomas of the breast. Herein, a rare case of invasive micropapillary carcinoma of the breast that was diagnosed via endometrial biopsy, without a previous diagnosis or history of breast cancer, was presented. A 58-year-old postmenopausal patient, who had no history of cancer, presented with complaints of abnormal uterine bleeding (AUB) that had begun 2 weeks prior. After undergoing transvaginal ultrasonography, endometrial biopsy, tomography, and positron emission tomography/computed tomography, the patient was preliminarily diagnosed with invasive carcinoma of the breast. The biopsy confirmed the diagnosis of metastatic invasive micropapillary carcinoma of the breast. In postmenopausal AUB, endometrial metastasis of breast cancer should be kept in mind, especially in underdeveloped and developing countries where regular breast cancer screening has not been achieved. KEY WORDS: Breast cancer, Endometrium, Metastasis, Micropapillary carcinoma.
乳腺癌转移至子宫较为罕见。大多数报道的病例均源自先前已知的浸润性乳腺导管癌和小叶癌。本文报道了一例罕见的经子宫内膜活检诊断的乳腺浸润性微乳头状癌病例,该患者既往无乳腺癌诊断或病史。一名 58 岁绝经后患者,无癌症病史,因 2 周前开始出现异常子宫出血(AUB)而就诊。经阴道超声、子宫内膜活检、断层扫描和正电子发射断层扫描/计算机断层扫描后,患者初步诊断为乳腺癌浸润性癌。活检证实为转移性乳腺浸润性微乳头状癌的诊断。在绝经后 AUB 中,应考虑到乳腺癌的子宫内膜转移,尤其是在尚未普及常规乳腺癌筛查的欠发达国家和发展中国家。
乳腺癌;子宫内膜;转移;微乳头状癌。