Liao Hailing, Hou Xiaorong, Chang Xiaoyan
Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P.R. China.
Department of Radiation Oncology, Pengshui Miao Tujia Autonomous County People's Hospital, Chongqing 409600, P.R. China.
Mol Clin Oncol. 2025 Mar 21;22(5):44. doi: 10.3892/mco.2025.2839. eCollection 2025 May.
Metastatic involvement of the reproductive system in patients with breast cancer is rare and has been reported only a few times in the literature. Notably, among patients without clinical symptoms, reproductive system metastases are easily overlooked and difficult to distinguish from primary tumors of the reproductive system, especially when the patient is receiving endocrine therapy. The prognosis of breast cancer is better than that of other aggressive cancers. However, if distant metastasis occurs, survival decreases greatly. In the present study, 2 cases of reproductive system metastasis from breast cancer were reported and the relevant literature was reviewed to provide support for the accurate diagnosis and appropriate treatment of affected patients.
乳腺癌患者出现生殖系统转移的情况较为罕见,文献中仅有少数几例报道。值得注意的是,在没有临床症状的患者中,生殖系统转移很容易被忽视,并且难以与生殖系统原发性肿瘤相区分,尤其是当患者正在接受内分泌治疗时。乳腺癌的预后优于其他侵袭性癌症。然而,如果发生远处转移,生存率会大幅下降。在本研究中,报告了2例乳腺癌生殖系统转移的病例,并对相关文献进行了综述,以为受影响患者的准确诊断和恰当治疗提供支持。