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乳腺癌转移至生殖系统:2例报告及文献复习:病例报告

Breast cancer metastasis to the reproductive system: Report of 2 cases and literature review: A case report.

作者信息

Liao Hailing, Hou Xiaorong, Chang Xiaoyan

机构信息

Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P.R. China.

Department of Radiation Oncology, Pengshui Miao Tujia Autonomous County People's Hospital, Chongqing 409600, P.R. China.

出版信息

Mol Clin Oncol. 2025 Mar 21;22(5):44. doi: 10.3892/mco.2025.2839. eCollection 2025 May.

DOI:10.3892/mco.2025.2839
PMID:40170684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11959219/
Abstract

Metastatic involvement of the reproductive system in patients with breast cancer is rare and has been reported only a few times in the literature. Notably, among patients without clinical symptoms, reproductive system metastases are easily overlooked and difficult to distinguish from primary tumors of the reproductive system, especially when the patient is receiving endocrine therapy. The prognosis of breast cancer is better than that of other aggressive cancers. However, if distant metastasis occurs, survival decreases greatly. In the present study, 2 cases of reproductive system metastasis from breast cancer were reported and the relevant literature was reviewed to provide support for the accurate diagnosis and appropriate treatment of affected patients.

摘要

乳腺癌患者出现生殖系统转移的情况较为罕见,文献中仅有少数几例报道。值得注意的是,在没有临床症状的患者中,生殖系统转移很容易被忽视,并且难以与生殖系统原发性肿瘤相区分,尤其是当患者正在接受内分泌治疗时。乳腺癌的预后优于其他侵袭性癌症。然而,如果发生远处转移,生存率会大幅下降。在本研究中,报告了2例乳腺癌生殖系统转移的病例,并对相关文献进行了综述,以为受影响患者的准确诊断和恰当治疗提供支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/11959219/6ca426cafeb2/mco-22-05-02839-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/11959219/d72c69a59e3e/mco-22-05-02839-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/11959219/6ca426cafeb2/mco-22-05-02839-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/11959219/d72c69a59e3e/mco-22-05-02839-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/11959219/6ca426cafeb2/mco-22-05-02839-g01.jpg

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CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322/caac.21834. Epub 2024 Apr 4.
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Comprehensive analysis of cancer of unknown primary and recommendation of a histological and immunohistochemical diagnostic strategy from China.中国不明原发癌的综合分析及组织学和免疫组织化学诊断策略推荐。
BMC Cancer. 2023 Dec 1;23(1):1175. doi: 10.1186/s12885-023-11563-1.
3
Uterine Metastasis Presenting as Abnormal Uterine Bleeding in a Case of Primary Breast Cancer Identified on F-FDG PET/CT.
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J Nucl Med Technol. 2023 Dec 5;51(4):333-334. doi: 10.2967/jnmt.123.266221.
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Tamoxifen use and risk of endometrial cancer in breast cancer patients: A systematic review and dose-response meta-analysis.他莫昔芬的使用与乳腺癌患者子宫内膜癌风险:系统评价和剂量反应荟萃分析。
Cancer Rep (Hoboken). 2023 Apr;6(4):e1806. doi: 10.1002/cnr2.1806. Epub 2023 Mar 14.
5
Comparison of GATA-3, Mammaglobin and GCDFP-15 Expression in Primary, Metastatic and Triple Negative Breast Carcinomas: An Indian Scenario.GATA-3、Mammaglobin 和 GCDFP-15 在原发性、转移性和三阴性乳腺癌中的表达比较:印度情况。
Asian Pac J Cancer Prev. 2023 Feb 1;24(2):509-515. doi: 10.31557/APJCP.2023.24.2.509.
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