Department of Tepecik Research and Training Hospital Ophthalmology, Izmir, Turkey.
Indian J Ophthalmol. 2021 Mar;69(3):630-634. doi: 10.4103/ijo.IJO_1061_20.
This study aimed to evaluate the optic coherence tomography (OCT) findings in patients with toxoplasmic retinochoroiditis (TRC).
A total of 12 eyes of 12 patients with active TRC were included in the study. At baseline, at the first-month follow-up, at the sixth-month follow-up and at the 1-year follow-up, the TRC lesion OCT and macula OCT were evaluated.
Hyperreflectivity of the inner retinal layers and an increase in retinal thickness were observed on the OCT examinations of all the patients with an active TRC lesion. The retinal thickness decreased and the reflectivity of retinal layers was disorganized in the OCT images obtained in the follow-up period. Partial posterior hyaloid detachment (PHD) and no PHD were detected in 11 cases and 1 case, respectively. Epiretinal membrane (ERM) had developed in the adjacent region of the scar in 7 patients. With the regression of the lesion, the disruption of the ellipsoid zone (EZ), retinal pigment epithelium (RPE) and external limiting membrane (ELM) improved in the adjacent areas. In all the eyes, ERM and the PHD configuration did progress during the follow-up period. Vitreoschisis was found in 4 of the 11 patients with partial PHD. It was observed that ERM developed in all the patients with vitreoschisis.
ERM and partial PHD were common in the TRC patients, and there was no progression during the follow-up period. Regeneration of the EZ, RPE and ELM was observed in the follow-up period.
本研究旨在评估弓形体性视网膜炎(TRC)患者的光相干断层扫描(OCT)结果。
本研究纳入了 12 例 12 只眼活动性 TRC 患者。在基线、第 1 个月随访、第 6 个月随访和第 1 年随访时,评估了 TRC 病变 OCT 和黄斑 OCT。
所有活动性 TRC 病变患者的 OCT 检查均显示内层视网膜高反射和视网膜增厚。在随访期间,视网膜厚度降低,视网膜层反射紊乱。11 例患者检测到部分后玻璃体脱离(PHD),1 例患者未检测到 PHD。7 例患者在瘢痕的邻近区域出现了视网膜内界膜(ERM)。随着病变的消退,邻近区域的椭圆体带(EZ)、视网膜色素上皮(RPE)和外界膜(ELM)的破坏得到改善。在所有患者中,ERM 和 PHD 的形态在随访期间都有进展。在 11 例部分 PHD 患者中,有 4 例发现玻璃体后脱离。所有玻璃体后脱离患者均观察到 ERM 形成。
ERM 和部分 PHD 在 TRC 患者中很常见,在随访期间没有进展。在随访期间观察到 EZ、RPE 和 ELM 的再生。