Tribe M J, Pinney R J
Antimicrob Agents Chemother. 1977 Oct;12(4):555-6. doi: 10.1128/AAC.12.4.555.
Thymine starvation of Escherichia coli strain C600 thy (R46) eliminated the R plasmid at a frequency of 17%. This was increased fourfold, to 68%, after the same culture was subjected to an additional three cycles of growth followed by thymineless death.
大肠杆菌C600 thy(R46)的胸腺嘧啶饥饿以17%的频率消除了R质粒。在同一培养物经历额外三个生长周期然后进行无胸腺嘧啶死亡后,这一频率增加了四倍,达到68%。