Department of Psychology, University of Maryland, College Park, MD, 20742, United States; Program in Neuroscience and Cognitive Science, University of Maryland, College Park, MD, 20742, United States.
Department of Psychology, University of Maryland, College Park, MD, 20742, United States; Program in Neuroscience and Cognitive Science, University of Maryland, College Park, MD, 20742, United States.
Behav Brain Res. 2021 Apr 23;404:113176. doi: 10.1016/j.bbr.2021.113176. Epub 2021 Feb 14.
The amygdala-one of the primary structures of the limbic system-is comprised of interconnected nuclei situated within the temporal lobe. It has a well-established role in the modulation of negative affective states, as well as in fear processing. However, its vast projections with diverse brain regions-ranging from the cortex to the brainstem-are suggestive of its more complex involvement in affective or motivational aspects of cognitive processing. The amygdala can play an invaluable role in context-dependent associative learning, unsigned prediction error learning, influencing outcome selection, and multidimensional encoding. In this review, we delve into the amygdala's role in associative learning and outcome selection, emphasizing its intrinsic involvement in the appropriate context-dependent modulation of motivated behavior.
杏仁核——边缘系统的主要结构之一——由位于颞叶内的相互连接的核组成。它在调节负面情绪状态以及恐惧处理方面具有明确的作用。然而,它与大脑各个区域(从皮层到脑干)的广泛投射表明,它在认知处理的情感或动机方面的参与更为复杂。杏仁核对上下文相关的联想学习、未签名预测误差学习、影响结果选择和多维编码具有重要作用。在这篇综述中,我们深入探讨了杏仁核对联想学习和结果选择的作用,强调了它在适当的上下文相关调节动机行为中的内在作用。