Kathrotiya Manthan, Radhakrishnan Vivek S, Bhave Saurabh J, Kumar Jeevan, Roychowdhury Mita, Arun Indu, Das Jayanta, Chandy Mammen, Nair Reena
Clinical Haematology Oncology and HCT Tata Medical Center Kolkata India.
Pathology Tata Medical Center Kolkata India.
Clin Case Rep. 2020 Dec 20;9(2):873-877. doi: 10.1002/ccr3.3673. eCollection 2021 Feb.
This case emphasizes that, with the availability of novel immunotherapy agents (Daratumumab), and repurposed use of bortezomib, a patient with HIV-negative relapsed PBL can be treated successfully and consolidated with an allogeneic haploidentical hematopoietic cell transplantation.
该病例强调,随着新型免疫治疗药物(达雷妥尤单抗)的出现以及硼替佐米的重新应用,一名HIV阴性的复发性原发性中枢神经系统淋巴瘤患者能够成功接受治疗,并通过异基因单倍体造血细胞移植进行巩固治疗。