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准分子激光角膜磨镶术治疗远视的同种异体角膜镶嵌术:28 只眼 1 年的临床结果。

Sterile Excimer Laser Shaped Allograft Corneal Inlay for Hyperopia: One-year Clinical Results in 28 Eyes.

机构信息

Faculty of Medicine, Ophthalmology Department, Medipol University, Istanbul, Turkey.

出版信息

Curr Eye Res. 2021 May;46(5):630-637. doi: 10.1080/02713683.2021.1884728. Epub 2021 Feb 18.

Abstract

: This study aimed to evaluate the one-year clinical results of an allograft corneal inlay (ACI) implantation in a case series of 28 hyperopic eyes of 16 patients.: Patients with manifest refraction spherical equivalent (MRSE) between +1.00 and +6.00 D and having a cylindrical refraction of less than 1 D were included in this prospective study. The refractive powers of excimer laser-shaped ACIs were determined based on the refractive error of the individual subject's eyes. After the creation of a femtosecond flap, the inlays were centered on the pupillary axis. Visual acuities, refractive results, and other clinical findings were reported for the 6- and 12-month follow-up exams.: The mean age of the patients included in the study was 36.2 ± 12.4 years (range 22-65 years). The mean pre-operative MSRE of 3.6 ± 1.51 D decreased to 0.21 ± 0.56 D ( < .001). The uncorrected distance and near visual acuity increased from 0.33 ± 0.22 and 0.17 ± 0.13 to 0.75 ± 0.22 ( < .001) and 0.72 ± 0.19 ( < .001), respectively. The corrected distance visual acuity remained unchanged (pre-OP: 0.79 ± 0.22; post-OP: 0.80 ± 0.21; = .916), and the corrected near visual acuity increased from 0.78 ± 0.22 to 0.84 ± 0.20 ( = .003). The mean K-value and central corneal thickness increased from 42.57 ± 0.81 D and 557.5 ± 43.0 µm to 44.8 ± 1.4 D ( < .001) and 597.1 ± 58.1 µm ( < .001), respectively. No significant postoperative complications such as diffuse lamellar keratitis, epithelial ingrowth, or decentralization were observed.: Excimer laser-shaped ACI offers an alternative treatment modality for patients with hyperopia. Acceptable visual results and similar regression rates were observed with ACI implantation compared with other laser refractive procedures.

摘要

本研究旨在评估一款同种异体角膜镶嵌物(ACI)在 16 名 28 只远视眼患者的病例系列中的一年临床效果。

本前瞻性研究纳入了等效球镜(MRSE)为+1.00 至+6.00 D,柱镜屈光度小于 1 D 的患者。准分子激光成形的 ACI 的屈光力基于个体受试者眼睛的屈光误差来确定。制作飞秒瓣后,将镶嵌物置于瞳孔轴的中心。在 6 个月和 12 个月的随访检查中报告了视力、屈光结果和其他临床发现。

研究纳入的患者平均年龄为 36.2±12.4 岁(22 至 65 岁)。术前平均等效球镜(MSRE)为 3.6±1.51 D,下降至 0.21±0.56 D(<.001)。未矫正远距和近距视力分别从 0.33±0.22 和 0.17±0.13 提高至 0.75±0.22(<.001)和 0.72±0.19(<.001)。矫正远距视力保持不变(术前:0.79±0.22;术后:0.80±0.21;=0.916),矫正近距视力从 0.78±0.22 提高至 0.84±0.20(=0.003)。平均 K 值和中央角膜厚度分别从 42.57±0.81 D 和 557.5±43.0 µm 增加至 44.8±1.4 D(<.001)和 597.1±58.1 µm(<.001)。未观察到弥漫性层间角膜炎、上皮内植入或偏心等术后严重并发症。

准分子激光成形的 ACI 为远视患者提供了一种替代治疗方法。与其他激光屈光手术相比,ACI 植入术后可获得可接受的视力结果和相似的回退率。

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