Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.
Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Acta Obstet Gynecol Scand. 2021 Apr;100(4):704-714. doi: 10.1111/aogs.14128.
Maternal near miss is a major global health issue; approximately 7 million women worldwide experience it each year. Maternal near miss can have several different health consequences and can affect the women's quality of life, yet little is known about the size and magnitude of this association. The aim of this study was to assess the evidence of the association between women who have experienced maternal near miss and quality of life and women who had an uncomplicated pregnancy and delivery.
Cochrane library, Embase, CINAHL, Web of Science, MEDLINE, Scopus and PubMed were searched for published studies. Studies were selected according to the PECO model (population, exposure, control and outcome) and were included if they investigated quality of life as an outcome after maternal near miss among women of all ages with no limitation on country or time (up to June 2020). Maternal near miss was defined as a life-threatening condition arising from complications related to pregnancy and/or childbirth. The quality of the studies was assessed according to the Newcastle-Ottawa scale and a Forest plot was constructed based on quality of life outcomes and study quality. PROSPERO registration number: CRD42020169232.
Fifteen studies were included in the review with a total of 31 558 women. Quality of life was reported in various ways, and 25 different confounders were controlled for. Compared with women who did not experience maternal near miss, women exposed to maternal near miss had an overall lower quality of life (n = 2/2), had poorer mental (n = 6/10) and social health (n = 2/3), and maternal near miss had negative economic consequences (n = 4/4). Maternal near miss was not associated with sexual dysfunction (n = 1/5). Ten of 15 studies were assessed as being of poor quality.
Evidence shows that maternal near miss is negatively associated with various aspects of quality of life. This highlights the importance of addressing the adverse effects associated with maternal near miss and follow up maternal near miss after discharge. Quality of life is a multidimensional concept that is assessed in various ways, and the literature on the field is heterogeneous. More high-quality studies are needed.
产妇严重并发症是一个全球性的主要健康问题;全世界每年约有 700 万妇女经历这种情况。产妇严重并发症可能会有多种不同的健康后果,并会影响妇女的生活质量,但人们对这种关联的规模和程度知之甚少。本研究的目的是评估经历产妇严重并发症的妇女与生活质量之间的关联的证据,以及经历无并发症妊娠和分娩的妇女。
在 Cochrane 图书馆、Embase、CINAHL、Web of Science、MEDLINE、Scopus 和 PubMed 上搜索已发表的研究。根据 PICO 模型(人群、暴露、对照和结局)选择研究,并纳入了所有年龄的妇女的生活质量作为产妇严重并发症的结局的研究,对国家和时间没有限制(截至 2020 年 6 月)。产妇严重并发症被定义为由妊娠和/或分娩相关并发症引起的危及生命的情况。根据 Newcastle-Ottawa 量表评估研究质量,并根据生活质量结局和研究质量构建森林图。PROSPERO 注册号:CRD42020169232。
该综述纳入了 15 项研究,共有 31558 名妇女。生活质量以各种方式报告,控制了 25 种不同的混杂因素。与未经历产妇严重并发症的妇女相比,经历产妇严重并发症的妇女的生活质量总体较低(n=2/2),心理健康(n=6/10)和社会健康(n=2/3)较差,产妇严重并发症对经济有负面影响(n=4/4)。产妇严重并发症与性功能障碍无关(n=1/5)。15 项研究中有 10 项被评估为质量较差。
证据表明,产妇严重并发症与生活质量的多个方面呈负相关。这突出表明,必须解决与产妇严重并发症相关的不利影响,并在出院后对产妇严重并发症进行随访。生活质量是一个多维的概念,以各种方式进行评估,该领域的文献存在异质性。需要更多高质量的研究。