Kneba M, Bergholz M, Schauer A, Nagel G A, Krieger G
Abteilung Hämatologie/Onkologie, Universität Göttingen.
Dtsch Med Wochenschr. 1988 Apr 15;113(15):602-4. doi: 10.1055/s-2008-1067690.
An anaplastic vaginal tumour was diagnosed in a 29-year-old woman. Before the planned operation leukocytosis and thrombocytopenia developed and further diagnostic tests revealed malignant histiocytosis with bone-marrow infiltration, leukaemic wash-out and tumour formation in the lower pelvis. Intensive chemotherapy, as for acute myeloid leukaemia, achieved full remission. The case demonstrates that, although rare, tumorous organ infiltration may be the initial manifestation of malignant histiocytosis. Its early diagnosis and treatment decisively affects the prognosis.
一名29岁女性被诊断出患有间变性阴道肿瘤。在计划手术前出现了白细胞增多和血小板减少,进一步的诊断检查显示为恶性组织细胞增多症,伴有骨髓浸润、白血病细胞清除及盆腔下部肿瘤形成。如同治疗急性髓细胞白血病一样进行强化化疗后实现了完全缓解。该病例表明,尽管罕见,但肿瘤性器官浸润可能是恶性组织细胞增多症的初始表现。其早期诊断和治疗对预后有决定性影响。