Asner Sandra A, Posfay-Barbe Klara M
Service de pédiatrie, Département femme-mère-enfant, CHUV, 1011 Lausanne.
Service de pédiatrie générale, Département de la femme, de l'enfant et de l'adolescent, HUG, 1211 Genève 14.
Rev Med Suisse. 2021 Feb 17;17(726):340-343.
Some uncertainties remain regarding SARS-CoV-2 diagnostic procedures and seroprevalence studies in children. RT-PCR assays conducted on nasopharyngeal (NP) swabs remain the gold standard for SARS-CoV-2 diagnostic in children as in adults. Saliva samples might replace soon NP swabs as similar sensitivities have been reported from both samples in adults, but not yet in children. Rapid antigen testing is currently performed on NP swabs collected from children within 4 days of their symptom onset. Serology testing is an essential diagnostic tool in seroprevalence studies, which might guide in the future public health decisions.
关于儿童中新型冠状病毒2型（SARS-CoV-2）的诊断程序和血清流行率研究仍存在一些不确定性。与成人一样，对鼻咽（NP）拭子进行的逆转录聚合酶链反应（RT-PCR）检测仍是儿童SARS-CoV-2诊断的金标准。唾液样本可能很快会取代NP拭子，因为在成人中已报告这两种样本的敏感性相似，但在儿童中尚未如此。目前在症状出现4天内从儿童采集的NP拭子上进行快速抗原检测。血清学检测是血清流行率研究中的一项重要诊断工具，这可能会为未来的公共卫生决策提供指导。
