Taylor H G, Stein C M, Jongeling G
Mpilo Hospital, Bulawayo, Zimbabwe.
Eur J Clin Pharmacol. 1988;34(1):87-90. doi: 10.1007/BF01061424.
Drug use before hospital admission was studied prospectively in 284 consecutive patients admitted to general medical wards in Zimbabwe. Drugs were used by 84% of patients. Self-medication was used by 143 (50%) patients, aspirin (54%) and chloroquine (17%) being the most commonly used drugs. Traditional medicines were used by 55 (19%) patients. Drugs dispensed from orthodox medical sources were taken by 128 (45%) patients. Analgesics (22%), antibiotics (18%), and chloroquine (13%) were the commonest drugs dispensed. Urine screening tests were performed and were positive for aspirin in 37% of cases, chloroquine (33%), and antibiotics (20%). Adverse drug reactions requiring hospital admission occurred in 14 patients (10 orthodox medicines, 4 traditional medicines). Drug use before hospital admission, which is often poorly documented, is a source of potential drug toxicity and may obscure a diagnosis of infective illness.
对津巴布韦综合内科病房收治的284例连续患者进行了入院前用药的前瞻性研究。84%的患者使用过药物。143例(50%)患者使用过自我药疗,其中阿司匹林(54%)和氯喹(17%)是最常用的药物。55例(19%)患者使用过传统药物。128例(45%)患者服用过正规医疗渠道配发的药物。配发最多的药物是镇痛药(22%)、抗生素(18%)和氯喹(13%)。进行了尿液筛查试验,结果显示37%的病例阿司匹林呈阳性,氯喹为33%,抗生素为20%。14例患者(10例因正规药物,4例因传统药物)因药物不良反应需住院治疗。入院前用药情况往往记录不完善,它是潜在药物毒性的一个来源,可能会掩盖感染性疾病的诊断。