Taylor H G, Stein C M, Jongeling G
Mpilo Hospital, Bulawayo, Zimbabwe.
Eur J Clin Pharmacol. 1988;34(1):87-90. doi: 10.1007/BF01061424.
Drug use before hospital admission was studied prospectively in 284 consecutive patients admitted to general medical wards in Zimbabwe. Drugs were used by 84% of patients. Self-medication was used by 143 (50%) patients, aspirin (54%) and chloroquine (17%) being the most commonly used drugs. Traditional medicines were used by 55 (19%) patients. Drugs dispensed from orthodox medical sources were taken by 128 (45%) patients. Analgesics (22%), antibiotics (18%), and chloroquine (13%) were the commonest drugs dispensed. Urine screening tests were performed and were positive for aspirin in 37% of cases, chloroquine (33%), and antibiotics (20%). Adverse drug reactions requiring hospital admission occurred in 14 patients (10 orthodox medicines, 4 traditional medicines). Drug use before hospital admission, which is often poorly documented, is a source of potential drug toxicity and may obscure a diagnosis of infective illness.
对津巴布韦综合内科病房收治的284例连续患者进行了入院前用药的前瞻性研究。84%的患者使用过药物。143例（50%）患者使用过自我药疗，其中阿司匹林（54%）和氯喹（17%）是最常用的药物。55例（19%）患者使用过传统药物。128例（45%）患者服用过正规医疗渠道配发的药物。配发最多的药物是镇痛药（22%）、抗生素（18%）和氯喹（13%）。进行了尿液筛查试验，结果显示37%的病例阿司匹林呈阳性，氯喹为33%，抗生素为20%。14例患者（10例因正规药物，4例因传统药物）因药物不良反应需住院治疗。入院前用药情况往往记录不完善，它是潜在药物毒性的一个来源，可能会掩盖感染性疾病的诊断。
