Holmberg L, Böttiger L E
Acta Med Scand. 1983;213(3):211-6. doi: 10.1111/j.0954-6820.1983.tb03719.x.
The drug consumption pattern and patients' knowledge about their drugs have been studied in 506 patients, acutely admitted to hospital. The patients took a mean of 3.2 drugs before hospitalization, the majority of them being used for more than one year. Calculated on all 506 interviewed patients, women took more drugs than men, but among the 406 users there was no significant difference in the number of drugs taken by men or women. The number of drugs increases markedly with age. The drugs most commonly used were digoxin (30% of the patients), nitrazepam (19%), furosemide (18%), potassium (17%) and nitroglycerin (14%). Dosage reduction with advancing age was registered i.a. for digoxin. Judging from the number of adverse drug reactions (ADRs) and subjective side-effects, the dosage reduction should probably have been even greater. Twenty-six patients (5%) were admitted because of an ADR, another 10 (2%) with an ADR. For the majority of drugs (84%) the patients had some understanding of the expected effect, but knowledge about possible side-effects was reported for 26% of the drugs only.
对506名急性入院患者的药物消费模式及患者对其所用药物的了解情况进行了研究。患者住院前平均服用3.2种药物，其中大多数已使用一年以上。按所有506名受访患者计算，女性服用的药物比男性多，但在406名用药者中，男性和女性服用药物的数量没有显著差异。药物数量随年龄显著增加。最常用的药物是地高辛（30%的患者）、硝西泮（19%）、呋塞米（18%）、钾（17%）和硝酸甘油（14%）。地高辛等药物的剂量随年龄增长而降低。从药物不良反应（ADR）和主观副作用的数量来看，剂量降低幅度可能还应更大。26名患者（5%）因药物不良反应入院，另有10名患者（2%）存在药物不良反应。对于大多数药物（84%），患者对预期效果有一定了解，但仅26%的药物有关于可能副作用的了解。
