Daifallah Aiman, Jabr Ruba, Al-Tawil Faraj, Elkourdi Moutaz, Salman Ziad, Koni Amer, Samara Ahmad, Al-Jabi Samah W, Zyoud Sa'ed H
Department of Clinical and Community Pharmacy, Department of Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.
Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.
BMC Public Health. 2021 Feb 18;21(1):380. doi: 10.1186/s12889-021-10432-5.
Paracetamol, also known as acetaminophen, is one of the most common antipyretic and analgesic over-the-counter (OTC) medicines administered to children due to its efficacy, safety, and availability in many pharmaceutical forms, including suppositories, syrup, and drops. Parents frequently administer the wrong dose of paracetamol by mistake for their children, as reported by many previous studies. We aimed in this study to assess parents' knowledge, attitudes, and practice regarding paracetamol dosing and toxicity, as well as their awareness regarding paracetamol-containing products.
This was a cross-sectional study that targeted parents of children seeking healthcare services at primary health care centers in the Nablus area in the West Bank, Palestine. We used questionnaire-based interviews with parents for data collection.
A total of 300 parents were included in the study. Most of the caregivers surveyed were (87%) females (mothers). About half the parents (50.9%) reported previously using paracetamol as an antipyretic in children under the age of six. A quarter (25.4%) preferred the syrup forms, while 33.8% preferred the suppository dosage form. Medical personnel was the primary source of information for half the caregivers (51.2%). The mean knowledge score about paracetamol was 2.1 (SD = 1.4) out of 6, and the median was 2.0 with an interquartile range of 1.0-3.0. Two hundred seventy-four (95.5%) of the participants scored less than 80% and were considered to have insufficient knowledge. Only 50.9% of parents recognized that paracetamol overdose could result in serious harm.
We found a serious lack of knowledge regarding paracetamol dosing, administration, and potential toxicity among Palestinian parents. We recommend raising awareness regarding this problem among healthcare providers and authorities and working on plans that aim to provide caregivers with accurate and adequate information on dosing, formulation, side effects, and other aspects of paracetamol use, as well as developing effective educational plans targeting healthcare providers, as well as the public.
对乙酰氨基酚,又称醋氨酚,是最常见的非处方(OTC)解热镇痛药之一,因其疗效、安全性以及有多种剂型(包括栓剂、糖浆和滴剂)可供使用,常被用于儿童。此前多项研究报告称,家长经常会误给孩子服用错误剂量的对乙酰氨基酚。本研究旨在评估家长关于对乙酰氨基酚剂量和毒性的知识、态度及做法,以及他们对含对乙酰氨基酚产品的认知。
这是一项横断面研究,目标人群是在巴勒斯坦约旦河西岸纳布卢斯地区初级卫生保健中心寻求医疗服务的儿童的家长。我们通过基于问卷的访谈对家长进行数据收集。
共有300名家长纳入本研究。接受调查的大多数照料者(87%)为女性(母亲)。约一半家长(50.9%)报告曾在6岁以下儿童中使用对乙酰氨基酚作为退烧药。四分之一(25.4%)的家长更喜欢糖浆剂型,而33.8%的家长更喜欢栓剂剂型。一半照料者(51.2%)的主要信息来源是医务人员。对乙酰氨基酚的平均知识得分在6分制中为2.1分(标准差 = 1.4),中位数为2.0,四分位间距为1.0 - 3.0。274名(95.5%)参与者得分低于80%,被认为知识不足。只有50.9%的家长认识到对乙酰氨基酚过量会导致严重伤害。
我们发现巴勒斯坦家长在对乙酰氨基酚的剂量、服用方法及潜在毒性方面严重缺乏知识。我们建议提高医疗服务提供者和当局对该问题的认识,并制定计划,旨在为照料者提供关于对乙酰氨基酚剂量、剂型、副作用及其他使用方面的准确和充分信息,同时制定针对医疗服务提供者及公众的有效教育计划。