Abd El-Aziz Esraa, Tahoun Mohamed M, Arafa Moustafa A, El-Banna Asmaa S
Epidemiology, High Institute of Public Health, Alexandria, EGY.
Forensic Medicine and Toxicology, Faculty of Medicine, Alexandria University, Alexandria, EGY.
Cureus. 2024 Jul 3;16(7):e63720. doi: 10.7759/cureus.63720. eCollection 2024 Jul.
Acute poisoning in children is a major public health problem worldwide. Children poisoning ranks among the top unintentional injuries in children aged less than four years. This paper aimed to describe the pattern and characteristics of acute poisoning incidents, estimate the percentage of medication poisoning among those children and highlight the possible risk factors. All children aged below 10 years admitted to Alexandria Poison Centre (APC) with acute poisoning from the July 1, 2022, to December 31, 2022, were included in the study. A pre-designed structured interviewing questionnaire was used to collect data: socio-demographic data of the poisoned child and his/her caregiver, medical history of the poisoned child and family members, history of previous poisoning incidents in the family, details of the poisoning incident including causative agent, route of poisoning, scene of poisoning, time interval to reach APC and the first aid done. 350 children admitted to APC were included in our study, of which 59% (n=208) of poisoned children were males with mean age 3.14 ± 2.28 years. The types of poisoning found were 46.6% chemical compounds, 31.4% medication, 18% household and 4% food poisoning. Most of the children were poisoned orally. High education of caregiver, urban residence and the presence of chronic disease within a family member were significantly associated with medication poisoning while low education of caregiver, drug addiction, having chronic disease among a family member and the presence of previous poisoning accident in the family were significantly associated with poisoning with chemical compounds. The study found that acute poisoning is more common among young male children in Alexandria; the chemical compounds came first as the main source of poisoning followed by the medication poisoning.
儿童急性中毒是全球主要的公共卫生问题。儿童中毒在4岁以下儿童的意外伤害中名列前茅。本文旨在描述急性中毒事件的模式和特征,估计这些儿童中药物中毒的百分比,并突出可能的风险因素。2022年7月1日至2022年12月31日入住亚历山大中毒中心(APC)的所有10岁以下急性中毒儿童均纳入本研究。使用预先设计的结构化访谈问卷收集数据:中毒儿童及其照顾者的社会人口学数据、中毒儿童和家庭成员的病史、家庭中先前中毒事件的历史、中毒事件的详细信息,包括致病剂、中毒途径、中毒现场、到达APC的时间间隔以及所做的急救。我们的研究纳入了350名入住APC的儿童,其中59%(n = 208)的中毒儿童为男性,平均年龄为3.14±2.28岁。发现的中毒类型为46.6%的化合物中毒、31.4%的药物中毒、18%的家用物品中毒和4%的食物中毒。大多数儿童为口服中毒。照顾者受教育程度高、城市居住以及家庭成员中有慢性病与药物中毒显著相关,而照顾者受教育程度低、药物成瘾、家庭成员中有慢性病以及家庭中曾发生中毒事故与化合物中毒显著相关。研究发现,亚历山大市的年幼男性儿童急性中毒更为常见;化合物中毒是中毒的主要来源,其次是药物中毒。