Gagal'chiĭ N G
Genetika. 1988 Feb;24(2):324-30.
Genetic variants of NADP+-dependent soluble isocitrate dehydrogenase (sIDH) expressed in pink salmon liver have been studied. The progeny of 16 individual crossings has been analysed. It is shown that sIDH in the liver of pink salmon is a dimer and is coded for by two duplicated loci, one of which is represented by 3 alleles (82, 100 and 124) and the other, probably by two (100 and 124). The products of the most frequently occurring alleles of these loci are almost similar in their electrophoretic mobility. Polypeptides coded for by the alleles of both loci combine freely, generating heterodimers.
对粉鲑肝脏中表达的烟酰胺腺嘌呤二核苷酸磷酸(NADP⁺)依赖性可溶性异柠檬酸脱氢酶(sIDH)的遗传变异进行了研究。分析了16个个体杂交的后代。结果表明,粉鲑肝脏中的sIDH是一种二聚体,由两个重复的基因座编码,其中一个基因座由3个等位基因(82、100和124)代表,另一个基因座可能由两个等位基因(100和124)代表。这些基因座最常见等位基因的产物在电泳迁移率上几乎相似。两个基因座等位基因编码的多肽可自由结合,形成异二聚体。