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不同类型黄斑裂孔的玻璃体切除术结果

Results of Pars Plana Vitrectomy for Different Types of Macular Holes.

作者信息

Ghoraba Hammouda Hamdy, Leila Mahmoud, Zaky Adel Galal, Wasfy Tamer, Maamoun Abdelfattah Haithem, Elgemai Emad Mohamed, Mohamed El Gouhary Sameh, Mansour Hosam Osman, Ghoraba Hashem Hammouda, Heikal Mohamed Amin

机构信息

Ophthalmology Department, Tanta University, Tanta City, Gharbia, Egypt.

Ophthalmology Department, Magrabi Eye Hospital, Tanta City, Gharbia, Egypt.

出版信息

Clin Ophthalmol. 2021 Feb 12;15:551-557. doi: 10.2147/OPTH.S290404. eCollection 2021.

Abstract

PURPOSE

To compare different types of macular holes regarding the anatomic and functional success following pars plana vitrectomy (PPV) and internal limiting membrane (ILM) removal.

METHODS

A retrospective review of all patients with macular holes treated by PPV, ILM removal with gas tamponade from January 2014 to July 2017 in Magrabi Eye Hospital.

RESULTS

One hundred fifty-seven eyes of 153 patients were analyzed. The eyes were classified according to the etiology of macular hole into four groups: 79 eyes with idiopathic macular hole (IMH), 51 eyes with traumatic macular hole (TMH), 16 eyes with macular hole in diabetic patients (DMH) and 11 eyes with myopic macular hole (MMH). We classified the IMH group based on the International Vitreomacular Traction Study Classification according to size into 3 subgroups; subgroup 1: ≤250µ, subgroup 2: >250 to 400µ and subgroup 3: ≥400 µ. All types of macular hole showed statistically significant postoperative improvement in BCVA compared to the baseline except cases with MMH. Anatomic postoperative hole closure was achieved in 86.1%, 60.7%, 43.65%, an 45.46% of eyes with IMH, TMH, DMH and MMH, respectively. In eyes with IMH, closure rate in subgroup 1 was significantly higher than in subgroups 2, and 3.

CONCLUSION

PPV, ILM peel and C2F6 technique yielded variable anatomic and functional outcomes in different types of macular holes. Anatomic results were most favorable in IMH and least favorable in MMH. The smaller the diameter of the hole the better the results. The underlying pathogenetic mechanisms that lead to different types of macular holes are pivotal in determining the final outcome.

摘要

目的

比较不同类型黄斑裂孔在玻璃体切割术(PPV)联合内界膜(ILM)剥除术后的解剖学和功能学成功率。

方法

回顾性分析2014年1月至2017年7月在马格拉比眼科医院接受PPV联合ILM剥除及气体填充治疗的所有黄斑裂孔患者。

结果

分析了153例患者的157只眼。根据黄斑裂孔的病因将这些眼分为四组:79只特发性黄斑裂孔(IMH)眼、51只外伤性黄斑裂孔(TMH)眼、16只糖尿病患者黄斑裂孔(DMH)眼和11只高度近视性黄斑裂孔(MMH)眼。我们根据国际玻璃体黄斑牵拉研究分类法将IMH组按大小分为3个亚组;亚组1:≤250µ,亚组2:>250至400µ,亚组3:≥400µ。除MMH病例外,所有类型的黄斑裂孔术后最佳矫正视力(BCVA)与基线相比均有统计学意义的改善。IMH、TMH、DMH和MMH眼的术后解剖学裂孔闭合率分别为86.1%、60.7%、43.65%和45.46%。在IMH眼中,亚组1的闭合率显著高于亚组2和3。

结论

PPV、ILM剥除和C2F6技术在不同类型的黄斑裂孔中产生了不同的解剖学和功能学结果。解剖学结果在IMH中最理想,在MMH中最不理想。裂孔直径越小,结果越好。导致不同类型黄斑裂孔的潜在发病机制在决定最终结果中起关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7550/7886253/64cd9c92271b/OPTH-15-551-g0001.jpg

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