Almousa Mandlin Abdulaziz, Alharbi Ghadah Khalid, Alqahtani Amerah Saeed, Chachar Yusra, Alkadi Lubna, Aboalela Ali
Dental Interns, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Saudi Pharm J. 2021 Jan;29(1):96-103. doi: 10.1016/j.jsps.2020.12.012. Epub 2020 Dec 29.
Medication-related osteonecrosis of the jaw (MRONJ) is a complication affecting patients who are being treated with antiresorptive or antiangiogenic medication. These patients require meticulous treatment planning and management strategies. This research aimed to assess the knowledge of dental practitioners and students in their professional years regarding MRONJ.
A cross-sectional study was conducted among 345 dental practitioners and students in their professional years of both genders, in governmental and private dental schools. The data was collected using an electronic and paper-based self-administered structured questionnaire with six sections. The data was entered and analyzed using SPSS Version 23, and a P-value <0.05 was considered significant. A Chi-square test was used to compare the categorical variables.
Though more than half of the sample 68% received information about antiresorptive and antiangiogenic drugs during their studies, the level of knowledge was low. The primary diseases targeted by antiresorptive and antiangiogenic medications were not known by the majority of the sample. Almost half of the sample could not identify any antiresorptive or antiangiogenic medication and only 28.1% knew the correct definition of MRONJ.
The level of knowledge regarding MRONJ is a concern, necessitating more educational courses and workshops.
药物性颌骨坏死（MRONJ）是一种影响正在接受抗吸收或抗血管生成药物治疗患者的并发症。这些患者需要精心的治疗计划和管理策略。本研究旨在评估牙科从业者和处于专业学习阶段的学生对MRONJ的了解情况。
对政府和私立牙科学校的345名处于专业学习阶段的男女牙科从业者和学生进行了一项横断面研究。数据通过一份包含六个部分的电子和纸质自填式结构化问卷收集。使用SPSS 23版软件录入和分析数据，P值<0.05被视为具有统计学意义。采用卡方检验比较分类变量。
尽管超过一半（68%）的样本在学习期间接受了关于抗吸收和抗血管生成药物的信息，但知识水平较低。大多数样本不知道抗吸收和抗血管生成药物所针对的主要疾病。几乎一半的样本无法识别任何抗吸收或抗血管生成药物，只有28.1%的人知道MRONJ的正确定义。
关于MRONJ的知识水平令人担忧，需要更多的教育课程和研讨会。
