Alghofaili Meshal M, Mohsin Syed Fareed, Nahari Nada Mohammed, Alkhalifah Tamim S, Almazyad Rayan Khaled, Alsaegh Mohammed K
Dentistry, Qassim University, Ar Rass, SAU.
Oral Maxillofacial Surgery and Diagnostic Sciences, Qassim University, Ar Rass, SAU.
Cureus. 2024 Jan 12;16(1):e52165. doi: 10.7759/cureus.52165. eCollection 2024 Jan.
Bisphosphonates (BPs) are often used in treating benign and malignant disorders. Medication-related osteonecrosis of the jaw (MRONJ) is a significant problem that arises from the long-term use of BPs.
In this study, we assessed the knowledge of students and dentists about MRONJ in the central region of Saudi Arabia.
A cross-sectional study was conducted to collect information from dental students and practitioners from the central region of Saudi Arabia. A valid, reliable, and structured questionnaire was used to gather data using a non-probability convenient sampling technique. IBM SPSS Statistics for Windows, Version 22.0 (Released 2013; IBM Corp., Armonk, New York, United States) was used to analyse the data. The descriptive data were expressed as frequencies and percentages to evaluate the association between dentists and students concerning overall knowledge related to osteonecrosis of the jaw, and a chi-squared test was applied.
In total, 250 individuals completed the questionnaire. The general knowledge of antiresorptive/antiangiogenic medications showed that most dentists (87.5%) and students (68.4%) knew about BP medications. A general lack of understanding about the therapeutic uses of antiangiogenic and antiresorptive medications was demonstrated by the participants. A significant proportion of dentists (58.8%) and students (50.9%) were not convinced that invasive dental procedures can be safely performed on patients receiving intravenous BP therapy. A significant proportion of the participants in the sample were unclear of the principal diseases that antiresorptive and antiangiogenic medications target. A mere 22% of respondents were aware of the accurate definition of medications-related MRONJ.
There is insufficient knowledge about MRONJ among students and practitioners. Therefore, these findings suggest increased emphasis should be placed on educating dentists and students about this condition to ensure patients receive the best possible care.
双膦酸盐(BPs)常用于治疗良性和恶性疾病。与药物相关的颌骨坏死(MRONJ)是长期使用双膦酸盐引发的一个重大问题。
在本研究中,我们评估了沙特阿拉伯中部地区学生和牙医对MRONJ的了解情况。
开展了一项横断面研究,以收集沙特阿拉伯中部地区牙科学生和从业者的信息。使用一份有效、可靠且结构化的问卷,通过非概率方便抽样技术收集数据。采用IBM SPSS Statistics for Windows 22.0版(2013年发布;IBM公司,美国纽约州阿蒙克)分析数据。描述性数据以频率和百分比表示,以评估牙医和学生在颌骨坏死相关总体知识方面的关联,并应用卡方检验。
共有250人完成了问卷。抗吸收/抗血管生成药物的一般知识显示,大多数牙医(87.5%)和学生(68.4%)了解双膦酸盐药物。参与者普遍对抗血管生成和抗吸收药物的治疗用途缺乏了解。相当比例的牙医(58.8%)和学生(50.9%)不相信对接受静脉注射双膦酸盐治疗的患者可以安全地进行侵入性牙科手术。样本中的相当一部分参与者不清楚抗吸收和抗血管生成药物所针对的主要疾病。只有22%的受访者知晓与药物相关的MRONJ的准确定义。
学生和从业者对MRONJ的了解不足。因此,这些研究结果表明应更加重视对牙医和学生进行关于这种疾病的教育,以确保患者得到尽可能好的护理。