妊娠合并慢性活动性乙型肝炎与新型冠状病毒肺炎：一例报告
Chronic Active Hepatitis B with COVID-19 in Pregnancy: A Case Report.
作者信息
Li Qiu-Yu, An Zhuo-Yu, Li Chao, Zu Ming, Chen Lei, Zhang Jia-Nan, Zhao Yang-Yu, Shen Ning, Ge Qing-Gang
机构信息
Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China.
Peking University Institute of Hematology, Peking University People's Hospital, Beijing, China.
出版信息
J Clin Transl Hepatol. 2021 Feb 28;9(1):133-135. doi: 10.14218/JCTH.2020.00085. Epub 2021 Jan 19.
Currently, infection with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during pregnancy is a problem worthy of attention, especially in patients with underlying diseases. In this case report, we present a case of chronic active hepatitis B with COVID-19 in pregnancy. A 31-year-old woman at 29 weeks of gestation who had a history of chronic hepatitis B virus infection discontinued antiviral treatment, was admitted to the hospital with chronic active hepatitis B, and tested positive for SARS-CoV-2 infection. In this case, we applied liver protective and antiviral agents, and low-dose dexamethasone therapy to successfully treat the critically ill pregnant woman suffering from chronic active hepatitis B combined with COVID-19.
目前，由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019冠状病毒病（COVID-19）感染在孕期是一个值得关注的问题，尤其是在患有基础疾病的患者中。在本病例报告中，我们呈现了一例妊娠期慢性活动性乙型肝炎合并COVID-19的病例。一名31岁、孕29周且有慢性乙型肝炎病毒感染病史的女性停止了抗病毒治疗，因慢性活动性乙型肝炎入院，并检测出SARS-CoV-2感染呈阳性。在此病例中，我们应用了肝保护剂和抗病毒药物以及小剂量地塞米松治疗，成功救治了这位患有慢性活动性乙型肝炎合并COVID-19的重症孕妇。
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