Jakobsen Nadia, Pedersen Marie Louise M, Amdi Charlotte
Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
SEGES Danish Pig Research Centre, Copenhagen, Denmark.
Transl Anim Sci. 2021 Jan 12;5(1):txab004. doi: 10.1093/tas/txab004. eCollection 2021 Jan.
The objective of this study was to investigate if iron can be allocated to piglets through sow milk replacer fed in a milk cup system with efficacies comparable to intramuscular (IM) administration of 200 mg gleptoferron. Two hundred and ninety-four piglets from 21 litters were allocated to three different iron treatments ( = 98). The treatments were 1) Control (CON) provided no supplemental iron, 2) Injected iron (II) provided 200 mg gleptoferron IM on day 3 postpartum, and 3) Milk iron (MI) provided sow milk replacer "DanMilk Supreme" added 1 % "Piglet Boozt" ad libitum from day 0 until 21 days postpartum. All piglets had access to dry feed from day 6. Initial and final body weight was registered and hemoglobin (Hb) levels were analyzed on day 0, 3, 7, 10, 17, and 21 after farrowing. In order to correlate drinking pattern with Hb level and growth, video cameras were installed, and drinking pattern was recorded on day 18 postpartum. A blood sample was drawn from piglets from three litters per treatment on day 21 for a complete hematology profile. The results showed that iron treatment had an effect on Hb levels ( < 0.001) that were different between all groups from day 10, resulting in a mean Hb level of 76.2 g/L (CON), 120.9 g/L (II), and 105.4 g/L (MI) on day 21. The mean Hb level for both MI and II was above the anemia threshold of 90 g/L and the Hb level of the II group was above 110 g/L and the piglets thus defined as normal. Treatment had a significant effect on Hb, hematocrit (hct), mean corposcular volume (MCV), mean corpuscular hemoglobin (MCH), red blood cell distribution width (RDW), lymphocytes (%), neutrophils (bill/L) ( < 0.05), neutrophils (%) ( < 0.01), with CON being significantly different from MI and II that were similar or tended to differ. Total visits at the cup was not correlated to Hb level ( = 0.08) and growth was not affected by treatment ( = 0.99). It is concluded that iron can be supplemented to piglets through a milk cup system with efficacies comparable to parenteral administration of 200 mg gleptoferron.
本研究的目的是调查在奶杯系统中通过给母猪饲喂代乳品是否能将铁分配给仔猪，其效果是否与肌肉注射200毫克葡聚糖铁相当。来自21窝的294头仔猪被分配到三种不同的铁处理组（每组 = 98头）。处理方式分别为：1）对照组（CON）不补充铁；2）注射铁组（II）在产后第3天肌肉注射200毫克葡聚糖铁；3）奶中铁组（MI）从产后第0天至第21天自由采食添加了1%“仔猪宝仔壮”的母猪代乳品“DanMilk Supreme”。所有仔猪从第6天开始可采食干饲料。记录初生和末重，并在分娩后第0、3、7、10、17和21天分析血红蛋白（Hb）水平。为了将饮水模式与Hb水平和生长情况相关联，安装了摄像机，并在产后第18天记录饮水模式。在第21天，从每个处理组的三窝仔猪中采集血样进行完整的血液学分析。结果表明，铁处理对Hb水平有影响（P < 0.001），从第10天起所有组之间存在差异，在第21天，对照组的平均Hb水平为76.2克/升，注射铁组为120.9克/升，奶中铁组为105.4克/升。奶中铁组和注射铁组的平均Hb水平均高于90克/升的贫血阈值，注射铁组的Hb水平高于110克/升，仔猪因此被定义为正常。处理对Hb、血细胞比容（hct）、平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH）、红细胞分布宽度（RDW）、淋巴细胞（%）、中性粒细胞（每升十亿个）（P < 0.05）、中性粒细胞（%）（P < 0.01）有显著影响，对照组与奶中铁组和注射铁组有显著差异，后两者相似或有差异趋势。奶杯处的总访问次数与Hb水平不相关（P = 0.08），生长不受处理影响（P = 0.99）。结论是，通过奶杯系统给仔猪补充铁的效果与肌肉注射200毫克葡聚糖铁相当。
