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腹腔镜袖状胃切除术术后早期袖状狭窄的技术因素影响:使用代谢和减重手术认证和质量改进计划数据库的分析。

Implications of Technical Factors in Development of Early Sleeve Stenosis After Laparoscopic Sleeve Gastrectomy: an Analysis Using the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program Database.

机构信息

Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

出版信息

Obes Surg. 2021 Jun;31(6):2373-2379. doi: 10.1007/s11695-021-05288-y. Epub 2021 Feb 18.

Abstract

PURPOSE

Laparoscopic sleeve gastrectomy (LSG) is the most commonly performed bariatric procedure worldwide. Sleeve stenosis (SS) is a rare complication of LSG and is associated with significant morbidity and economic burden. The objective of this study was to determine the prevalence and impact of early SS and identify technical factors which may predict its development.

MATERIALS AND METHODS

Data was extracted from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) data registry from 2015 to 2018. Patients undergoing primary LSG were included, while patients undergoing revisional bariatric surgery were excluded. A multivariable logistic regression analysis was performed to identify technical factors associated with SS.

RESULTS

A total of 389,839 patients (79.4% female) were included with a mean age of 44.2 ± 12.0 years and mean body mass index of 45.1 ± 7.8 kg/m. SS was rare, occurring in only 0.09% (n=345) of patients within 30 days of the operation. Following multivariable analysis, technical factors associated with early SS included prolonged operative time > 60 min (OR 1.32, 95% CI 1.17-1.48, p < 0.001) and a shorter PD (OR 0.864, 95% CI 0.784-0.951, p=0.003). For every 1-cm increase in PD, the odds of SS decreased by 13.6%.

CONCLUSION

Overall, early SS is a rare complication, affecting only 0.09% of patients undergoing primary LSG. Technical factors associated with 30-day SS included PD and operative time. Though current guidelines suggest a PD as short as 2 cm, our findings suggest this may be associated with an increased risk of early postoperative SS.

摘要

目的

腹腔镜袖状胃切除术(LSG)是目前全球应用最广泛的减重手术。袖状胃狭窄(SS)是 LSG 的一种罕见并发症,与显著的发病率和经济负担相关。本研究旨在确定早期 SS 的发生率和影响,并确定可能预测其发展的技术因素。

材料和方法

数据来自 2015 年至 2018 年的代谢和减重手术认证和质量改进计划(MBSAQIP)数据库。纳入初次接受 LSG 的患者,排除接受减重手术修正的患者。采用多变量逻辑回归分析确定与 SS 相关的技术因素。

结果

共纳入 389839 例患者(79.4%为女性),平均年龄为 44.2±12.0 岁,平均 BMI 为 45.1±7.8kg/m²。SS 罕见,仅在术后 30 天内发生在 0.09%(n=345)的患者中。多变量分析后,与早期 SS 相关的技术因素包括手术时间延长>60 分钟(OR 1.32,95%CI 1.17-1.48,p<0.001)和 PD 缩短(OR 0.864,95%CI 0.784-0.951,p=0.003)。PD 每增加 1cm,SS 的可能性就降低 13.6%。

结论

总体而言,早期 SS 是一种罕见的并发症,仅影响 0.09%接受初次 LSG 的患者。与 30 天 SS 相关的技术因素包括 PD 和手术时间。尽管目前的指南建议 PD 最短为 2cm,但我们的研究结果表明,这可能与早期术后 SS 的风险增加有关。

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