POEMS 综合征的神经超声研究。
Nerve ultrasound studies in POEMS syndrome.
机构信息
Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
出版信息
Muscle Nerve. 2021 May;63(5):758-764. doi: 10.1002/mus.27209. Epub 2021 Mar 6.
INTRODUCTION
The aim of our study was to assess the ultrasonographic features of peripheral nerves in patients with POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) syndrome.
METHOD
34 POEMS syndrome patients and 26 healthy control (HC) participants were recruited prospectively. Cross-sectional area (CSA) was measured in nerves of limbs, trunks of brachial plexus, and cervical nerve roots RESULTS: The CSAs were mildly enlarged at the arm segment of median nerve, elbow segment of ulnar nerve and upper trunk, moderately enlarged at the forearm segment of both median and ulnar nerve, upper trunk of brachial plexus, and C6, C7 cervical nerve roots, and markedly enlarged at the arm segment of ulnar nerve, middle and lower trunk of brachial plexus, as well as C5 cervical root.
DISCUSSION
The CSAs of upper limb nerves were larger in POEMS syndrome patients than in HCs, and the enlargements were most prominent proximally.
简介
本研究旨在评估 POEMS（多发性神经病、器官肿大、内分泌病、M 蛋白和皮肤改变）综合征患者外周神经的超声特征。
方法
前瞻性纳入 34 例 POEMS 综合征患者和 26 名健康对照者（HC）。测量四肢、臂丛干和颈神经根神经的横截面积（CSA）。
结果
正中神经臂段、尺神经肘段和上干、正中神经和尺神经前臂段、臂丛上干和 C6、C7 颈神经根 CSA 轻度增大，尺神经臂段、臂丛中干和下干以及 C5 颈神经根 CSA 中度增大。
讨论
POEMS 综合征患者上肢神经 CSA 大于 HC，且近端增大多见于近端。
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