Department of Urology, Clinica Universidad de Navarra, University of Navarra, Pamplona, Spain.
Department of Urology, Complejo Asistencial Universitario de León, León, Spain.
Neurourol Urodyn. 2021 Mar;40(3):840-847. doi: 10.1002/nau.24631. Epub 2021 Feb 19.
To identify the definition for urinary continence (UC) after radical prostatectomy (RP) which reflects best patients' perception of quality of life (QoL).
Continence was prospectively assessed in 634 patients, 12 months after RP using the International Consultation on Incontinence Questionnaire Short-Form (ICIQ-SF) and the number of pads employed in a 24-hour period (pad usage). We used the one-way ANOVA technique with posthoc pairwise comparisons according to Scheffé's method (homogeneous subsets) for assessing the degree of QoL deficit related to urinary incontinence (UI).
The continence prevalence is 64.4%, 74.1%, 88.3%, and 35.8% using "0 pads," "1 safety pad," "1 pad," and "ICIQ score 0" definitions, respectively. Pad usage is moderately strongly associated with ICIQ 1, 2, and 3 (ρ = 0.744, 0.677, and 0.711, respectively; p < 0.001). Concordance between classical UC definitions is acceptable between "0 pads-ICIQ score 0" (K = 0.466), but poor for "1 safety pad" and "1 pad" (K = 0.326 and 0.137, respectively). Patients with "0 pad usage" have better QoL related to urine leakage than patients with "1 safety pad" or "1 pad" (1.41 vs. 2.44 and 3.11, respectively; p < 0.05). There were no significant differences found regarding QoL between patients with ICIQ score 0 and ICIQ score 2 (1.01 vs. 1.63; p = 0.63).
Pad usage and the ICIQ-SF's answers provide useful information. We propose a combined definition (0 pads and ICIQ score ≤2) as it is the definition with the least impact on daily QoL.
确定根治性前列腺切除术(RP)后尿控的定义,该定义最好能反映患者对生活质量(QoL)的感知。
634 例 RP 术后 12 个月的患者前瞻性使用国际尿失禁咨询问卷简表(ICIQ-SF)和 24 小时内使用的尿垫数量评估尿控。我们使用单向方差分析技术,根据 Scheffé 方法(同质子集)进行事后两两比较,评估与尿失禁(UI)相关的 QoL 缺陷程度。
使用“0 个尿垫”、“1 个安全尿垫”、“1 个尿垫”和“ICIQ 评分 0”的定义,尿控的发生率分别为 64.4%、74.1%、88.3%和 35.8%。尿垫使用与 ICIQ 1、2 和 3 中度强相关(ρ=0.744、0.677 和 0.711,均 P<0.001)。经典 UC 定义之间的一致性在“0 个尿垫-ICIQ 评分 0”之间可接受(K=0.466),但在“1 个安全尿垫”和“1 个尿垫”之间较差(K=0.326 和 0.137)。“0 个尿垫使用”的患者与“1 个安全尿垫”或“1 个尿垫”的患者相比,漏尿相关的 QoL 更好(分别为 1.41、2.44 和 3.11,均 P<0.05)。ICIQ 评分 0 和 ICIQ 评分 2 的患者 QoL 之间无显著差异(1.01 和 1.63;P=0.63)。
尿垫使用和 ICIQ-SF 的答案提供了有用的信息。我们提出了一个联合定义(0 个尿垫和 ICIQ 评分≤2),因为它对日常 QoL 的影响最小。