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根治性前列腺切除术后尿失禁的管理:挑战与解决方案

Management of Urinary Incontinence Following Radical Prostatectomy: Challenges and Solutions.

作者信息

Castellan Pietro, Ferretti Simone, Litterio Giulio, Marchioni Michele, Schips Luigi

机构信息

Department of Urology, ASL02 Abruzzo, Chieti, Italy.

Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University of Chieti, Urology Unit, Chieti, Italy.

出版信息

Ther Clin Risk Manag. 2023 Jan 15;19:43-56. doi: 10.2147/TCRM.S283305. eCollection 2023.

Abstract

Urinary incontinence is a common and debilitating problem in patients undergoing radical prostatectomy. Current methods developed to treat urinary incontinence include conservative treatments, such as lifestyle education, pelvic muscle floor training, pharmacotherapy, and surgical treatments, such as bulking agents use, artificial urinary sphincter implants, retrourethral transobturator slings, and adjustable male sling system. Pelvic floor muscle exercise is the most common management to improve the strength of striated muscles of the pelvic floor to try to recover the sphincter weakness. Antimuscarinic drugs, phosphodiesterase inhibitors, duloxetine, and a-adrenergic drugs have been proposed as medical treatments for urinary incontinence after radical prostatectomy. Development of new surgical techniques, new surgical tools and materials, such as male slings, has provided an improvement of outcomes after UI surgery. Such improvement is still ongoing, and the uptake of new devices might lead to even better outcomes after UI surgery.

摘要

尿失禁是接受根治性前列腺切除术患者中常见且使人虚弱的问题。目前开发的治疗尿失禁的方法包括保守治疗,如生活方式教育、盆底肌肉训练、药物治疗,以及手术治疗,如使用填充剂、植入人工尿道括约肌、经闭孔后尿道吊带和可调节男性吊带系统。盆底肌肉锻炼是最常见的治疗方法,旨在增强盆底横纹肌的力量,以试图恢复括约肌功能障碍。抗胆碱能药物、磷酸二酯酶抑制剂、度洛西汀和α-肾上腺素能药物已被提议作为根治性前列腺切除术后尿失禁的药物治疗方法。新手术技术、新手术工具和材料(如男性吊带)的开发,已使尿失禁手术后的疗效得到改善。这种改善仍在进行中,新设备的应用可能会使尿失禁手术后取得更好的疗效。

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