Chambers J, Whaley A, Campbell S
Cardiac Unit, King's College Hospital, London, U.K.
Int J Cardiol. 1988 Mar;18(3):427-32. doi: 10.1016/0167-5273(88)90061-7.
A 65-year-old female, presenting 32 weeks after mitral valve replacement with malaise and weight loss, was found to have a massive left atrial thrombus. She was treated successfully with streptokinase 1,000,000 units followed by anticoagulation with heparin then warfarin. The Doppler ultrasound recordings of left ventricular inflow were biphasic on admission but had resumed a normal appearance 11 days afterwards when clot retraction had occurred. We suggest that thrombolysis should be considered as alternative therapy in patients thought too frail for surgery.
一名65岁女性，在二尖瓣置换术后32周出现不适和体重减轻，被发现有巨大的左心房血栓。她接受了100万单位链激酶的成功治疗，随后用肝素抗凝，然后用华法林。入院时左心室流入道的多普勒超声记录呈双相，但在11天后血栓回缩时恢复了正常外观。我们建议，对于被认为身体过于虚弱而无法进行手术的患者，应考虑将溶栓作为替代治疗方法。
