Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Division of Anatomical Pathology, Department of Pathology and Laboratory Medicine, Dalhousie University, Halifax, Canada.
Am J Dermatopathol. 2021 Sep 1;43(9):e104-e106. doi: 10.1097/DAD.0000000000001925.
Whipple disease (WD) is a rare bacterial infectious disease that is classically characterized by years of arthralgia, followed by malabsorption, diarrhea, and weight loss. However, WD may manifest in virtually any organ system, and patients with WD rarely develop subcutaneous erythema nodosum-like lesions. We report a case of a 51-year-old man diagnosed with WD who subsequently developed widely distributed erythematous subcutaneous nodules after 5 months of antibiotic therapy.
惠普尔病(WD)是一种罕见的细菌性传染病,其特征为多年的关节痛,随后出现吸收不良、腹泻和体重减轻。然而,WD 几乎可以在任何器官系统中表现出来,WD 患者很少出现皮下结节样红斑。我们报告了一例 51 岁男性 WD 患者的病例,在接受抗生素治疗 5 个月后,他随后出现广泛分布的红色皮下结节。