IEEE Trans Biomed Eng. 2021 May;68(5):1702-1713. doi: 10.1109/TBME.2021.3060541. Epub 2021 Apr 21.
Biopsies are the gold standard for clinical diagnosis. However, a discrepancy between the biopsy sample and target tissue because of misplacement of the biopsy spoon can lead to errors in the diagnosis and subsequent treatment. Thus, correctly determining whether the needle tip is in the tumor is crucial for accurate biopsy results.
A biopsy needle system was designed with a steerable, flexible, and superelastic concentric tube; electrodes to monitor the electrical resistivity; and load cells to monitor the insertion force. The degrees of freedom were analyzed for two working modes: straight-line and deflection.
Experimental results showed that the system could perceive the tissue type in online based on the electrical resistivity. In addition, changes in the insertion force indicated transitions between the interfaces of adjacent tissue layers.
The two monitoring methods guarantee that the biopsy spoon is at the desired position inside the tumor during an operation.
The proposed biopsy needle system can be integrated into an autonomous robotic biopsy system.
活检是临床诊断的金标准。然而,由于活检勺的错位,活检样本与目标组织之间存在差异,可能导致诊断和后续治疗出现错误。因此,正确确定针尖是否位于肿瘤内对于准确的活检结果至关重要。
设计了一种带有可转向、灵活和超弹性同心管的活检针系统;电极用于监测电阻率;以及负载细胞用于监测插入力。分析了两种工作模式(直线和转向)的自由度。
实验结果表明,该系统可以根据电阻率在线感知组织类型。此外,插入力的变化表明相邻组织层界面之间的转变。
这两种监测方法可确保活检勺在手术过程中处于肿瘤内的预期位置。
所提出的活检针系统可以集成到自主机器人活检系统中。