Department of Mechanical, Materials and Aerospace Engineering, School of Engineering, University of Liverpool, Liverpool, United Kingdom.
Department of Engineering and Technology, School of Physics, Engineering & Computer Science, University of Hertfordshire, Hatfield, United Kingdom.
PLoS One. 2021 Feb 19;16(2):e0247194. doi: 10.1371/journal.pone.0247194. eCollection 2021.
To investigate the stress-strain behaviour of 9 soft contact lens materials, that are commonly used in the market, under uniaxial compression loading.
Seven types of hydrogel and two types of silicone-hydrogel soft contact lens materials were hydrated in phosphate-buffered saline (PBS) solution then subjected to uniaxial compression loads. The load rate was set to 16.0 N/min starting with two consecutive initial 5.0 N loading cycles followed by three relaxation periods of 4.0 min within which there were two more 5.0 N loading cycles and eventually, a full loading cycle that stopped at a load of 49.0 N. The load and contraction data obtained experimentally were analysed to derive the stress-strain behaviour. Finite Element (FE) analysis was then utilised to evaluate the performance of soft contact lenses on the human eye and handling lenses off the eye.
Unlike tensile tests, all tested materials showed nonlinear behaviour when tested under compression. When fitted to first-order Ogden hyperelastic model, parameter μ was found to be varying in the range 0.12 to 0.74 MPa and material parameter α was found to be varying in the range 8.2 to 20.326 among the nine tested materials. Compression modulus of elasticity was 2.2 times higher than the tensile modulus of elasticity on average. FE simulation with nonlinear Ogden constitutive model showed a limited change (8%~12%) in the optical performance when compared to other material models, however, it predicted higher stress when the lens was simulated under bending during off-eye handling.
Compression tests revealed slightly nonlinear behaviour when materials were strained under compression stress down to 15% ~ 30% of their nominal heights. Considering the physiological compression loading range of 8 mmHg, secant moduli of elasticity were 1.5% to 6.9% higher than the tension moduli of elasticity depending on the material. Tensile-based moduli of elasticity could be used in FE analysis as a step towards simulating the optical performance of soft contact lenses on-eye. However, nonlinear compression-based material models are recommended for FE analysis of soft contact lenses when lens-handling is investigated off-eye.
研究 9 种市售软性隐形眼镜材料在单轴压缩载荷下的应力-应变行为。
将 7 种水凝胶和 2 种硅水凝胶软性隐形眼镜材料在磷酸盐缓冲盐水 (PBS) 溶液中水化,然后施加单轴压缩载荷。加载速率设定为 16.0 N/min,包括两个连续的初始 5.0 N 加载循环,随后进行三个 4.0 min 的松弛周期,在此期间进行另外两个 5.0 N 的加载循环,最终完成一个完整的加载循环,加载停止在 49.0 N。从实验中获得的载荷和收缩数据进行分析,得出应力-应变行为。然后利用有限元 (FE) 分析评估软性隐形眼镜在人眼上的性能和从眼睛上取下隐形眼镜的操作。
与拉伸试验不同,所有测试材料在压缩试验下均表现出非线性行为。当拟合到一阶 Ogden 超弹性模型时,发现参数 μ 的变化范围为 0.12 至 0.74 MPa,材料参数 α 的变化范围为 8.2 至 20.326,在 9 种测试材料中。压缩弹性模量平均比拉伸弹性模量高 2.2 倍。使用非线性 Ogden 本构模型的 FE 模拟显示,与其他材料模型相比,光学性能的变化有限(8%~12%),然而,当在模拟取下隐形眼镜时的眼内弯曲时,预测的应力更高。
当材料在压缩应力下应变至其名义高度的 15%30%时,压缩试验显示出略微的非线性行为。考虑到生理压缩载荷范围为 8 mmHg,基于切线的弹性模量比拉伸弹性模量高 1.5%6.9%,具体取决于材料。基于拉伸的弹性模量可用于 FE 分析,以模拟软性隐形眼镜的光学性能。然而,当研究眼外隐形眼镜操作时,建议使用非线性压缩基材料模型进行软性隐形眼镜的 FE 分析。