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Rates of Major Cardiovascular Events in Severe Asthma: U.S. Real-World and Clinical Trial-Eligible Populations.

作者信息

Dayal Parul, Iribarren Carlos, Cheung Dorothy, Rothenberg Michael E, Spain C Victor

机构信息

Genentech Inc. South San Francisco, California.

Kaiser Permanente Northern California Oakland, California.

出版信息

Ann Am Thorac Soc. 2021 Sep;18(9):1580-1584. doi: 10.1513/AnnalsATS.202010-1349RL.

DOI:10.1513/AnnalsATS.202010-1349RL
PMID:33606957
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8489874/
Abstract
摘要

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2
Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study in moderate to severe asthma.接受奥马珠单抗治疗的患者中的心血管和脑血管事件:来自 EXCELS 的结果,一项中度至重度哮喘的前瞻性队列研究。
J Allergy Clin Immunol. 2017 May;139(5):1489-1495.e5. doi: 10.1016/j.jaci.2016.07.038. Epub 2016 Sep 14.
3
A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results.关于随机对照试验样本代表性及其对试验结果外部有效性影响的文献综述。
Trials. 2015 Nov 3;16:495. doi: 10.1186/s13063-015-1023-4.
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A rule of thumb for estimating the lower confidence interval in trials with small event rates.一种用于估计小事件发生率试验中置信区间下限的经验法则。
Anaesthesia. 2015 Aug;70(8):1008-10. doi: 10.1111/anae.13169.
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Asthma predicts cardiovascular disease events: the multi-ethnic study of atherosclerosis.哮喘预示心血管疾病事件:动脉粥样硬化的多民族研究。
Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1520-5. doi: 10.1161/ATVBAHA.115.305452. Epub 2015 Apr 23.
6
If a little bit is wrong, how much is alright? Interpreting the significance of small numerators in clinical trials.若有一点差错,那多大程度算合适?解读临床试验中小分子的意义。
Anaesthesia. 2015 Mar;70(3):249-52. doi: 10.1111/anae.12980. Epub 2014 Dec 23.
7
Adult asthma and risk of coronary heart disease, cerebrovascular disease, and heart failure: a prospective study of 2 matched cohorts.成人哮喘与冠心病、脑血管病和心力衰竭风险:2 项匹配队列的前瞻性研究。
Am J Epidemiol. 2012 Dec 1;176(11):1014-24. doi: 10.1093/aje/kws181. Epub 2012 Nov 8.
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Informing evidence-based decision-making for patients with comorbidity: availability of necessary information in clinical trials for chronic diseases.为合并症患者提供循证决策信息:慢性病临床试验中必要信息的可用性。
PLoS One. 2012;7(8):e41601. doi: 10.1371/journal.pone.0041601. Epub 2012 Aug 3.
9
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JAMA. 2007 Mar 21;297(11):1233-40. doi: 10.1001/jama.297.11.1233.
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Thorax. 2007 Mar;62(3):219-23. doi: 10.1136/thx.2006.066837. Epub 2006 Nov 14.