Robinson K, Huntington K M, Wallace M G
Br J Obstet Gynaecol. 1977 Oct;84(10):784-8. doi: 10.1111/j.1471-0528.1977.tb12493.x.
A placebo-controlled, randomized, double-blind, parallel group study in hospital and general practice has shown that a combination of belladonna alkaloids, ergotamine tartrate, and phenobarbitone (Bellergal) was effective in treating troublesome symptoms of the premenstrual syndrome of which fatigue, tender breasts, nervousness, irritability, lethargy and listlessness were improved to a statistically significant degree. The drug was given three times daily and caused no side effects.
一项在医院和普通诊所进行的安慰剂对照、随机、双盲、平行组研究表明，颠茄生物碱、酒石酸麦角胺和苯巴比妥（Bellergal）的组合对治疗经前综合征的棘手症状有效，其中疲劳、乳房胀痛、紧张、易怒、无精打采和倦怠等症状有统计学显著改善。该药物每日服用三次，且无副作用。
