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伴C1脱位及C2齿状突破坏的陈旧性脊柱结核的治疗:1例报告

The management of neglected spondylitis tuberculosis with dislocated C1 and C2 odontoid destruction: A case report.

作者信息

Harun Jursal, Akbar Danar Lukman

机构信息

Department of Orthopaedic and Traumatology, Indonesia Army Central Hospital, Indonesia.

Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Indonesia.

出版信息

Int J Surg Case Rep. 2021 Mar;80:105606. doi: 10.1016/j.ijscr.2021.01.100. Epub 2021 Feb 6.

Abstract

INTRODUCTION AND IMPORTANCE

Spinal tuberculosis was the most common TB infection in human body. Musculoskeletal tuberculosis (TB) mostly affected lower thoracal or upper lumbar spine. However, TB infection can also occurs along vertebral spine. We reported a rare case about TB infection in cervical spine. We provided the clinical manifestation and therapeutic method for the patient. Cervical TB infection is a very rare case. Especially, when it involves in C1 and C2 like we provided on this case.

CASE PRESENTATION

A 24 years-old male came to the orthopaedic clinic with neck pain that aggravated by neck movement. He previously diagnosed with TB infection on his lung within 3 months. We performed x-ray data to determine the source of neck pain. Examination revealed anterior collapse of C1, destruction of odontoid process, and soft tissue swelling. We also performed MRI cervical to assess the destruction of anterior corpus C1.

CLINICAL DISCUSSION

We decided to operate the patient with reposition and posterior stabilization of C1 using occipital plate from posterior approach and added some synthetic bone graft. The medical treatment is anti-tuberculosis drugs, usually conducted conservatively in mild-to-moderate cases. But, if there is deterioration in neurological deficit or persisting deficit with spinal cord compression, such as C1 and C2 involvement, surgery can be considered. There are two types of surgery; posterior fixation and fusion and anterior release and posterior stabilization.

CONCLUSION

TB musculoskeletal infection must be evaluated regularly to consider the perfect time for additional surgical treatment. The good decision to operate the moderate to severe case could improve the patient's functional outcome.

摘要

引言与重要性

脊柱结核曾是人体最常见的结核感染。肌肉骨骼结核大多累及下胸椎或上腰椎。然而,结核感染也可沿脊柱发生。我们报告了一例罕见的颈椎结核感染病例。我们提供了该患者的临床表现及治疗方法。颈椎结核感染是非常罕见的病例。特别是像我们在此病例中所呈现的累及C1和C2的情况。

病例介绍

一名24岁男性因颈部活动时疼痛加剧前来骨科门诊。他在3个月内曾被诊断出肺部有结核感染。我们进行了X线检查以确定颈部疼痛的病因。检查发现C1椎体前缘塌陷、齿突破坏以及软组织肿胀。我们还进行了颈椎MRI检查以评估C1椎体前部的破坏情况。

临床讨论

我们决定对患者进行手术,采用后路枕骨板对C1进行复位和后路固定,并添加一些人工骨移植。药物治疗为抗结核药物,在轻至中度病例中通常采用保守治疗。但是,如果神经功能缺损恶化或存在脊髓受压导致的持续性缺损,如累及C1和C2,则可考虑手术。手术有两种类型:后路固定融合术和前路松解后路固定术。

结论

必须定期评估肌肉骨骼结核感染情况,以确定进行额外手术治疗的最佳时机。对中重度病例做出手术的正确决策可改善患者的功能预后。

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