与同种异体移植供体和受体淋巴细胞混合培养上清液孵育的巨噬细胞中溶酶体酶的减少。
Decrease of lysosomal enzymes in macrophages incubated with supernatants of mixed culture of allograft donor and recipient lymphocytes.
作者信息
Dy M, Kamoun P
出版信息
Biomedicine. 1977 Jul;27(5):181-2.
PMID:336108
Abstract
Incubation of mouse peritoneal macrophages (thioglycollate-induced) for 72 hours with the supernatant of a mixed lymphocyte culture (MLC) between skin allograft donor and recipient results in a decrease of macrophage acid phosphatase (EC 3.1.3.2.) and beta glucuronidase (EC 3.2.1.31). The alteration of these lysosomal enzymes is not explained by a loss of cell viability.
摘要
将皮肤同种异体移植供体和受体之间的混合淋巴细胞培养（MLC）上清液与小鼠腹腔巨噬细胞（经巯基乙酸诱导）一起孵育72小时，会导致巨噬细胞酸性磷酸酶（EC 3.1.3.2.）和β-葡萄糖醛酸酶（EC 3.2.1.31）减少。这些溶酶体酶的改变并非由细胞活力丧失所致。
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