Mavier P, Dubois M, Dy M
Ann Immunol (Paris). 1979 Jan-Feb;130C(1):85-9.
Using a test proposed in this laboratory for following macrophage "activation" (intracellular beta-glucuronidase content) and quantitative dilution studies, we have shown that lymphocytes from mice presensitized by a skin allograft release far more macrophage activating lympholines than do normal lymphocytes when non-specifically stimulated by concanavalin A. This difference may be due to latent metabolic changes of sensitized lymphocytes, but it may also express a modified balance among the various lymphocyte subpopulations within the spleen of grafted mice.
利用本实验室提出的一项用于追踪巨噬细胞“激活”（细胞内β-葡萄糖醛酸酶含量）的检测方法以及定量稀释研究，我们发现，经皮肤同种异体移植预先致敏的小鼠的淋巴细胞，在受到伴刀豆球蛋白A非特异性刺激时，释放的巨噬细胞激活淋巴细胞比正常淋巴细胞多得多。这种差异可能是由于致敏淋巴细胞潜在的代谢变化，但也可能反映了移植小鼠脾脏内各种淋巴细胞亚群之间经改变的平衡。
