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B淋巴细胞抗原(类IA)的阳性交叉配型与肾移植行为

Positive cross-match for B-lymphocyte antigens (IA like) and kidney allograft behaviour.

作者信息

Soulillou J P, Guenel J, Peyrat M A

出版信息

Biomedicine. 1977 Jul;27(5):183-4.

PMID:336109
Abstract

We describe six cases of kidney graft performed against a positive anti-B lymphocyte cross-match. These antibodies were found after retrospective and systematic screening of the effect of the recipient sera upon donor frozen B lymphocytes. As opposed to the consequences of anti-HLA "SD" preimmunisation, none of the transplantation rapported here failed by acute rejection. The benefic role of anti-B lymphocyte antibodies "Ia like" present at the time of grafting is then suggested.

摘要

我们描述了6例在抗B淋巴细胞交叉配型阳性情况下进行的肾移植病例。这些抗体是在对受者血清对供者冷冻B淋巴细胞的作用进行回顾性系统筛查后发现的。与抗HLA“SD”预免疫的后果相反,此处报告的移植均未因急性排斥反应而失败。由此提示移植时存在的抗B淋巴细胞“类Ia”抗体具有有益作用。

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