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胃黏膜鳞状上皮化生伴淋巴瘤浸润。

Squamous Metaplasia of the Stomach Associated with Lymphoma Infiltration.

机构信息

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan.

Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.

出版信息

Intern Med. 2021 Jul 15;60(14):2229-2234. doi: 10.2169/internalmedicine.6271-20. Epub 2021 Feb 22.

Abstract

We herein report a patient who presented with follicular lymphoma. Although the stomach was initially intact, mucosal redness and multiple erosions appeared in the gastric body owing to infiltration of the follicular lymphoma cells. Subsequently, a slightly depressed, white area lacking gastric mucosal structure was detected in the lesser curvature of the gastric cardia and body, where lymphoma cell infiltration was also pathologically observed beneath the stratified squamous epithelium. This case indicated that, although infrequent, prolonged mucosal injury owing to lymphoma infiltration can cause squamous metaplasia in the stomach.

摘要

我们在此报告一例以滤泡性淋巴瘤为表现的患者。尽管胃最初是完整的,但由于滤泡性淋巴瘤细胞的浸润,胃体出现黏膜红斑和多个糜烂。随后,在胃贲门和体部小弯侧发现一稍凹陷、白色区域,缺乏胃黏膜结构,其下方的复层鳞状上皮中也存在淋巴瘤细胞浸润。本例表明,尽管罕见,但淋巴瘤浸润引起的长期黏膜损伤可导致胃的鳞状上皮化生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc9e/8355407/de0d0ce916a3/1349-7235-60-2229-g001.jpg

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