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忘掉磷吧:一例维生素D过量引起的症状性高钙血症病例。

Forget the phosphorus: A case of hypervitaminosis D-induced symptomatic hypercalcemia.

作者信息

Nguyen Todd, Joe Deanna, Shah Ankur D

机构信息

The Warren Alpert Medical School of Brown University.

Department of Internal Medicine.

出版信息

Clin Nephrol Case Stud. 2021 Feb 9;9:1-3. doi: 10.5414/CNCS110414. eCollection 2021.

Abstract

Hypercalcemia is a frequently encountered electrolyte abnormality with a well-described differential diagnosis and classic algorithm for evaluation. The treatment for hypercalcemia is dependent on the underlying etiology. Hypervitaminosis D is an uncommon cause of hypercalcemia, but the use of vitamin D supplementation has expanded and case reports of supplemental vitamin D induced hypercalcemia have become more frequent. We present a case of hypervitaminosis D-induced altered mental status where diagnosis was delayed and additional invasive testing was performed due to an assumption regarding phosphatemia.

摘要

高钙血症是一种常见的电解质异常,其鉴别诊断明确,评估有经典的算法。高钙血症的治疗取决于潜在病因。维生素D过多症是高钙血症的罕见病因,但维生素D补充剂的使用有所增加,补充维生素D引起高钙血症的病例报告也越来越常见。我们报告一例维生素D过多症导致精神状态改变的病例,由于对血磷的假设,诊断延迟并进行了额外的侵入性检查。

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本文引用的文献

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Hypercalcemia: a consultant's approach.高钙血症:顾问的方法。
Pediatr Nephrol. 2018 Sep;33(9):1475-1488. doi: 10.1007/s00467-017-3788-z. Epub 2017 Sep 6.
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FGF23 and Phosphate Wasting Disorders.成纤维细胞生长因子 23 与磷酸盐丢失性疾病。
Bone Res. 2013 Jun 28;1(2):120-32. doi: 10.4248/BR201302002. eCollection 2013 Jun.
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Laboratory approaches for the diagnosis and assessment of hypercalcemia.用于高钙血症诊断和评估的实验室方法。
Crit Rev Clin Lab Sci. 2015;52(3):107-19. doi: 10.3109/10408363.2014.970266. Epub 2014 Oct 20.
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Phosphate metabolism and vitamin D.磷代谢与维生素D
Bonekey Rep. 2014 Feb 5;3:497. doi: 10.1038/bonekey.2013.231. eCollection 2014.
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Investigation of hypercalcemia.高钙血症的调查。
Clin Biochem. 2012 Aug;45(12):954-63. doi: 10.1016/j.clinbiochem.2012.04.025. Epub 2012 May 5.

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