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1
[Diabetes mellitus in childhood and adolescence (Update 2019)].儿童及青少年糖尿病(2019年更新版)
Wien Klin Wochenschr. 2019 May;131(Suppl 1):85-90. doi: 10.1007/s00508-018-1420-2.
2
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis.儿科糖尿病酮症酸中毒输液速度的临床试验。
N Engl J Med. 2018 Jun 14;378(24):2275-2287. doi: 10.1056/NEJMoa1716816.
3
Potential Clinical Benefits of a Two-bag System for Fluid Management in Pediatric Intensive Care Unit Patients with Diabetic Ketoacidosis.两袋系统在小儿重症监护病房糖尿病酮症酸中毒患者液体管理中的潜在临床益处。
Pediatr Endocrinol Diabetes Metab. 2017;23(1):6-13. doi: 10.18544/PEDM-23.01.0068.
4
A randomized controlled trial of one bag vs. two bag system of fluid delivery in children with diabetic ketoacidosis: Experience from a developing country.一项关于在糖尿病酮症酸中毒患儿中应用一袋与两袋补液系统的随机对照试验:来自发展中国家的经验。
J Crit Care. 2018 Feb;43:340-345. doi: 10.1016/j.jcrc.2017.09.175. Epub 2017 Sep 22.
5
Effect of Volume of Fluid Resuscitation on Metabolic Normalization in Children Presenting in Diabetic Ketoacidosis: A Randomized Controlled Trial.液体复苏量对糖尿病酮症酸中毒患儿代谢正常化的影响:一项随机对照试验
J Emerg Med. 2016 Apr;50(4):551-9. doi: 10.1016/j.jemermed.2015.12.003. Epub 2016 Jan 25.
6
Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial.儿科糖尿病酮症酸中毒、液体疗法和脑损伤:一项析因随机对照试验的设计。
Pediatr Diabetes. 2013 Sep;14(6):435-46. doi: 10.1111/pedi.12027. Epub 2013 Mar 13.
7
Subclinical cerebral edema in children with diabetic ketoacidosis randomized to 2 different rehydration protocols.糖尿病酮症酸中毒患儿随机分为 2 种不同补液方案后的亚临床脑水肿。
Pediatrics. 2013 Jan;131(1):e73-80. doi: 10.1542/peds.2012-1049. Epub 2012 Dec 10.
8
Evaluation of the two-bag system for fluid management in pediatric patients with diabetic ketoacidosis.两袋系统用于小儿糖尿病酮症酸中毒患者液体管理的评估。
J Pediatr Pharmacol Ther. 2009 Apr;14(2):100-5. doi: 10.5863/1551-6776-14.2.100.
9
A prospective study of the "two-bag system'' in diabetic ketoacidosis management.糖尿病酮症酸中毒管理中“双袋系统”的前瞻性研究。
Clin Pediatr (Phila). 2004 Nov-Dec;43(9):809-13. doi: 10.1177/000992280404300904.
10
Risk factors for developing brain herniation during diabetic ketoacidosis.糖尿病酮症酸中毒期间发生脑疝的危险因素。
Pediatr Neurol. 1999 Oct;21(4):721-7. doi: 10.1016/s0887-8994(99)00079-x.

用于糖尿病酮症酸中毒患儿静脉输液管理的双袋系统:来自一家社区医院的经验

The Two-bag System for Intravenous Fluid Management of Children with Diabetic Ketoacidosis: Experience from a Community-Based Hospital.

作者信息

Hasan Rashed A, Hamid Kewan, Dubre Donald, Nolan Brian, Sharman Mahesh

机构信息

St Vincent Mercy Children's Hospital, Toledo, OH, USA.

Saint Peter's University Hospital, New Brunswick, NJ, USA.

出版信息

Glob Pediatr Health. 2021 Jan 24;8:2333794X21991532. doi: 10.1177/2333794X21991532. eCollection 2021.

DOI:10.1177/2333794X21991532
PMID:33614853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7841651/
Abstract

Intravenous fluid (IVF) administration using the two-bag system compared with the one-bag system in children with diabetic ketoacidosis (DKA) admitted between January 1, 2015 and December 31, 2016. Retrospective cohort study. Community-based hospital. A total of 109 patients were enrolled with a mean age of 13.24 years. The 2 groups had comparable demographics. Initial laboratory results were similar except for initial PH and Sodium. The two bag system had significantly less number of calls compared to one bag system (25.2 vs 5.2  = .0001). One bag system had fewer hypoglycemia <60 mg/dl (4 vs 12  = .049). No statistically significant observations noted in regards to glucose drop rate, number of intravenous fluid bags used, amount of fluid boluses given, hospital stay and Pediatric ICU stay. The two-bag system has less resource utilization and slower blood glucose drop rate, but higher hypoglycemic events.

摘要

2015年1月1日至2016年12月31日期间收治的糖尿病酮症酸中毒(DKA)患儿中,使用双袋系统与单袋系统进行静脉输液(IVF)给药的比较。回顾性队列研究。社区医院。共纳入109例患者,平均年龄13.24岁。两组人口统计学特征具有可比性。除初始pH值和钠含量外,初始实验室结果相似。与单袋系统相比,双袋系统的呼叫次数明显更少(25.2比5.2,P = 0.0001)。单袋系统低血糖<60mg/dl的情况较少(4例比12例,P = 0.049)。在血糖下降速率、使用的静脉输液袋数量、给予的液体推注量、住院时间和儿科重症监护病房住院时间方面,未观察到统计学上的显著差异。双袋系统资源利用率较低,血糖下降速率较慢,但低血糖事件较多。