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儿童及青少年糖尿病(2019年更新版)

[Diabetes mellitus in childhood and adolescence (Update 2019)].

作者信息

Rami-Merhar Birgit, Fröhlich-Reiterer Elke, Hofer Sabine E

机构信息

Universitätsklinik für Kinder- und Jugendheilkunde, Medizinische Universität Wien, Wien, Österreich.

Universitätsklinik für Kinder- und Jugendheilkunde, Medizinische Universität Graz, Graz, Österreich.

出版信息

Wien Klin Wochenschr. 2019 May;131(Suppl 1):85-90. doi: 10.1007/s00508-018-1420-2.

Abstract

In contrast to adults, type 1 diabetes mellitus (T1D) is the most frequent form of diabetes in childhood and adolescence (>95%). After diagnosis the management of children and adolescents with T1D should take place in highly specialized pediatric units experienced in pediatric diabetology and not in private practices. The lifelong substitution of insulin is the cornerstone of treatment whereby modalities need to be individually adapted for patient age and the family routine. Diabetes education is essential in the management of patients with diabetes and their families and needs to be performed by a multidisciplinary team consisting of a pediatric endocrinologist, diabetes educator, dietitian, psychologist and social worker. The Austrian working group for pediatric endocrinology and diabetes (APEDÖ) recommends a metabolic goal of HbA1c ≤7.0%, International Federation for Clinical Chemistry (IFCC) <53 mmol/mol, for all pediatric age groups without the presence of severe hypoglycemia. Age-related physical, cognitive and psychosocial development, avoidance of acute diabetes-related complications (severe hypoglycemia, diabetic ketoacidosis) and prevention of diabetes-related late complications to ensure high quality of life are the main goals of diabetes treatment in all pediatric age groups.

摘要

与成人不同,1型糖尿病(T1D)是儿童和青少年中最常见的糖尿病类型(>95%)。确诊后,患有T1D的儿童和青少年应在有儿科糖尿病专业经验的高度专业化儿科单位接受治疗,而不是在私人诊所。胰岛素的终身替代是治疗的基石,治疗方式需要根据患者年龄和家庭日常情况进行个体化调整。糖尿病教育对于糖尿病患者及其家庭的管理至关重要,需要由包括儿科内分泌学家、糖尿病教育者、营养师、心理学家和社会工作者在内的多学科团队来进行。奥地利儿科内分泌学和糖尿病工作组(APEDÖ)建议,在无严重低血糖的情况下,所有儿科年龄组的糖化血红蛋白(HbA1c)代谢目标为≤7.0%,国际临床化学联合会(IFCC)标准为<53 mmol/mol。与年龄相关的身体、认知和心理社会发育,避免急性糖尿病相关并发症(严重低血糖、糖尿病酮症酸中毒)以及预防糖尿病相关晚期并发症以确保高质量生活,是所有儿科年龄组糖尿病治疗的主要目标。

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