Živković Krešimir, Marton Ingrid, Tikvica Luetić Ana, Gašparov Slavko, Horvat Pavlov Katarina, Sović Ljudevit, Cerovac Anis, Habek Dubravko
"Sveti Duh" University Hospital, Department of Obstetrics and Gynecology, University of Zagreb, School of Medicine, Zagreb, Croatia.
"Sveti Duh" University Hospital, Department of Obstetrics and Gynecology, Catholic University of Croatia, Zagreb, Croatia.
Wien Med Wochenschr. 2022 May;172(7-8):181-183. doi: 10.1007/s10354-021-00823-z. Epub 2021 Feb 22.
Ovarian lymphoma is a rare neoplasm and most commonly represents secondary ovarian involvement in overt systemic disease, usually of the non-Hodgkin's type.
To report a case of acute abdomen caused by torquated large ovarian lymphoma.
We report the case of 65-year-old patient admitted to our hospital with signs and symptoms of acute abdomen. Findings were suggestive of left ovary torsion due to the neoplasm. After detorsion, mobilization, and adhesiolysis, a bilateral adnexectomy was performed. Histopathological and immunohistochemical analysis of the left ovarian tumor was performed and diagnosis of diffuse large B‑cell lymphoma (DLBCL) with a GCB (germinal center B‑cell-like) phenotype was made. Additional bone marrow biopsy and imaging techniques excluded other sites of involvement, confirming diagnosis of primary ovarian DLBCL.
The prognosis of ovarian lymphomas may be poorer than for other lymphomas because of late diagnosis. The best treatment option appears to be systemic chemotherapy.
卵巢淋巴瘤是一种罕见的肿瘤，最常见的是在明显的全身性疾病中表现为卵巢继发性受累，通常是非霍奇金淋巴瘤类型。
报告一例因巨大卵巢淋巴瘤扭转导致急腹症的病例。
我们报告了一名65岁患者因急腹症症状和体征入院。检查结果提示肿瘤导致左卵巢扭转。在扭转复位、活动和粘连松解后，进行了双侧附件切除术。对左侧卵巢肿瘤进行了组织病理学和免疫组化分析，诊断为具有生发中心B细胞样（GCB）表型的弥漫性大B细胞淋巴瘤（DLBCL）。额外的骨髓活检和影像学检查排除了其他受累部位，确诊为原发性卵巢DLBCL。
由于诊断较晚，卵巢淋巴瘤的预后可能比其他淋巴瘤更差。最佳治疗选择似乎是全身化疗。
