Arnogiannaki N, Grigoriadis C, Zygouris D, Androutsopoulos G, Derdelis G, Terzakis E
Department of Pathology, St. Savvas Anticancer-Oncologic Hospital, Athens, Greece.
Eur J Gynaecol Oncol. 2011;32(4):441-2.
Primary ovarian non Hodgkin's lymphoma (PONHL) is a very rare disease. We present a case of PONHL and review the literature.
The patient, a 24-year-old nulliparous Greek woman, presented with the complaint of abdominal pain. She underwent left salpingo-oophorectomy, multiple biopsies from the right ovary, total omentectomy, pelvic and paraortic lymphadenectomy, appendectomy and curettage. The histopathology revealed diffuse large B-cell non-Hodgkin's lymphoma of the left ovary. She underwent postoperative chemotherapy. She remains well without evidence of disease, 15 months after initial surgery.
The use of chemotherapy is based on the principle that PONHL must be considered a localized manifestation of systemic disease. Patients with PONHL have a similar outcome compared to patients with other NHL.
原发性卵巢非霍奇金淋巴瘤(PONHL)是一种非常罕见的疾病。我们报告一例PONHL病例并复习相关文献。
患者为一名24岁未生育的希腊女性,主诉腹痛。她接受了左侧输卵管卵巢切除术、右侧卵巢多次活检、全大网膜切除术、盆腔及腹主动脉旁淋巴结切除术、阑尾切除术和刮宫术。组织病理学显示左侧卵巢弥漫性大B细胞非霍奇金淋巴瘤。她接受了术后化疗。初次手术后15个月,她情况良好,无疾病迹象。
化疗的应用基于PONHL必须被视为系统性疾病的局部表现这一原则。与其他非霍奇金淋巴瘤患者相比,PONHL患者的预后相似。