Am J Trop Med Hyg. 2021 Feb 22;104(4):1321-1325. doi: 10.4269/ajtmh.20-1297.
A delay in diagnosis and initiation of treatment in patients with tuberculosis (TB) can affect the period of communicability and cost of treatment. We aimed to describe the diagnostic pathways and delays in initiation of treatment among drug-sensitive newly diagnosed TB patients in Ballabgarh, India. In May 2019, we interviewed 110 TB patients who were put on treatment in the past 2 months. It was a cross-sectional study where data collection was conducted by a physician. We used a structured questionnaire to collect the information on care-seeking practices, delays, and patient's cost. Descriptive analysis was carried out for the pathways, delays, and patient cost. The mean number of health facility contacted before the diagnosis of TB was 2.8 (SD: 1.3); 76% of patients first sought care at a private health facility. The median total delay was 34.5 (IQR: 21-60) days; median patient delay seven (IQR: 2-21) days, median health system delay 16 (IQR: 8-45) days, median diagnostic delay 32.5 (IQR: 18-57) days, and median treatment delay two (IQR: 1-3) days. Health system delay was 2.2 times longer than patient delay; the health system delay was primarily due to delay in diagnosis. Patients contacting private health facility first had 1.7 times total delay, 2.4 times longer health system delay, and 3.4 times of direct cost compared with patients contacting a public health facility first. Accelerated efforts are needed to achieve India's target to eliminate TB by 2025.
诊断和开始治疗结核病(TB)患者的延迟会影响传染性和治疗成本。我们旨在描述印度巴拉伯格地区新诊断的药物敏感型 TB 患者的诊断途径和治疗延迟。2019 年 5 月,我们对过去 2 个月内接受治疗的 110 名 TB 患者进行了访谈。这是一项横断面研究,由医生进行数据收集。我们使用结构化问卷收集了有关寻求治疗、延迟和患者费用的信息。对途径、延迟和患者费用进行了描述性分析。在诊断 TB 之前,患者平均接触的医疗机构数量为 2.8(SD:1.3);76%的患者首次在私人医疗机构寻求治疗。中位总延迟为 34.5(IQR:21-60)天;中位患者延迟 7(IQR:2-21)天,中位卫生系统延迟 16(IQR:8-45)天,中位诊断延迟 32.5(IQR:18-57)天,中位治疗延迟 2(IQR:1-3)天。卫生系统延迟是患者延迟的两倍;卫生系统延迟主要是由于诊断延迟。首先联系私人医疗机构的患者总延迟增加了 1.7 倍,卫生系统延迟增加了 2.4 倍,直接费用增加了 3.4 倍,与首先联系公共卫生机构的患者相比。需要加快努力,以实现印度到 2025 年消除结核病的目标。