Liu Siyuan, Qiao Yanan, Wu Ying, Shen Yueping, Ke Chaofu
Department of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, China.
Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
J Psychiatr Res. 2021 Apr;136:217-223. doi: 10.1016/j.jpsychires.2021.02.039. Epub 2021 Feb 16.
This study aimed to prospectively assess the relationship between depressive symptoms and change in self-rated health (SRH) in middle-aged and elderly Chinese adults.
We used data from the China Health and Retirement Longitudinal Study (CHARLS). The final analysis included 8169 participants (≥45 years old) and a multinomial logistic regression model was used to assess the association between baseline depression and follow-up change in SRH.
Taking no change in SRH as the reference, depressive symptoms at baseline were positively associated with a 2-year decline in SRH (OR: 1.38, 95% CI: 1.15-1.65) and negatively associated with a 2-year improvement in SRH (OR: 0.74, 95% CI: 0.63-0.85). Over a 4-year period, the OR (95% CI) values increased to 1.41 (1.19-1.67) and decreased to 0.69 (0.59-0.80) for decline and improvement in SRH, respectively. In stratified analyses, the association between depression and 2- or 4-year decline/improvement in SRH persisted in all sex and age subgroups.
Baseline depression is an independent predictor of change in SRH among Chinese people aged 45 and above. Early monitoring and management of depressive symptoms may be worthwhile to maintain and improve SRH in the middle-aged and elderly population.
本研究旨在前瞻性评估中国中老年成年人抑郁症状与自评健康状况(SRH)变化之间的关系。
我们使用了中国健康与养老追踪调查(CHARLS)的数据。最终分析纳入了8169名参与者(年龄≥45岁),并使用多项逻辑回归模型评估基线抑郁与随访时SRH变化之间的关联。
以SRH无变化为参照,基线时的抑郁症状与SRH在2年内下降呈正相关(比值比:1.38,95%置信区间:1.15 - 1.65),与SRH在2年内改善呈负相关(比值比:0.74,95%置信区间:0.63 - 0.85)。在4年期间,SRH下降和改善的比值比(95%置信区间)值分别增至1.41(1.19 - 1.67)和降至0.69(0.59 - 0.80)。在分层分析中,抑郁与SRH在2年或4年的下降/改善之间的关联在所有性别和年龄亚组中均持续存在。
基线抑郁是45岁及以上中国人SRH变化的独立预测因素。对抑郁症状进行早期监测和管理可能有助于维持和改善中老年人群的SRH。