Showa University Head and Neck Oncology Centre, Tokyo, Japan; Department of Oral and Maxillofacial Surgery, Division of Oral Oncology, Showa University, School of Dentistry, Tokyo, Japan.
Showa University Head and Neck Oncology Centre, Tokyo, Japan; Department of Oral and Maxillofacial Surgery, Division of Oral Oncology, Showa University, School of Dentistry, Tokyo, Japan.
Int J Oral Maxillofac Surg. 2021 Nov;50(11):1408-1412. doi: 10.1016/j.ijom.2021.02.001. Epub 2021 Feb 19.
The objective of this study was to investigate the accuracy of fine needle aspiration cytology (FNAC) and biopsy for the clinical diagnosis of minor salivary gland tumours (MSGTs). This retrospective study of 32 MSGT cases was conducted over a 5-year period. Clinical features including age, sex, and location of the tumour were obtained from the patient clinical records. All cases were also assessed histologically according to the 2017 World Health Organization Classification of Head and Neck Tumours. The results of FNAC and biopsy were correlated with those of histopathology, and their sensitivity, specificity, and diagnostic efficacy were calculated using histopathology as the gold standard. Eighteen malignant MSGTs (56.3%) and 14 benign MSGTs (43.8%) were diagnosed by pathological diagnosis. The most common malignant tumour was mucoepidermoid carcinoma (seven cases, 38.9%). Most benign cases were pleomorphic adenomas (13 cases, 92.9%). FNAC was performed for 23 cases and biopsy for 13 cases. The sensitivity and specificity of FNAC were 66.7% and 91.0%, respectively, while those of biopsy were 90.0% and 100.0%, respectively. Although FNAC is a minimally invasive and cost-effective procedure, it is less accurate than biopsy in the assessment of MSGTs. Repeated FNAC or biopsy should be considered in negative and unsatisfactory FNAC cases.
本研究旨在探讨细针穿刺细胞学（FNAC）和活检对小唾液腺肿瘤（MSGT）临床诊断的准确性。这项回顾性研究共纳入 32 例 MSGT 病例，研究时间为 5 年。从患者的临床记录中获取了年龄、性别和肿瘤位置等临床特征。所有病例还根据 2017 年世界卫生组织头颈部肿瘤分类进行了组织学评估。FNAC 和活检的结果与组织病理学结果相关联，并以组织病理学为金标准计算了它们的敏感性、特异性和诊断效能。通过病理诊断，18 例恶性 MSGT（56.3%）和 14 例良性 MSGT（43.8%）得到诊断。最常见的恶性肿瘤是黏液表皮样癌（7 例，38.9%）。大多数良性病例为多形性腺瘤（13 例，92.9%）。对 23 例病例进行了 FNAC，对 13 例病例进行了活检。FNAC 的敏感性和特异性分别为 66.7%和 91.0%，活检的敏感性和特异性分别为 90.0%和 100.0%。虽然 FNAC 是一种微创且具有成本效益的程序，但在评估 MSGT 方面不如活检准确。在 FNAC 结果为阴性和不满意的情况下，应考虑重复进行 FNAC 或活检。
