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队列简介:南澳大利亚原住民出生队列(SAABC)——一个前瞻性纵向出生队列。

Cohort profile: South Australian Aboriginal Birth Cohort (SAABC)-a prospective longitudinal birth cohort.

作者信息

Jamieson Lisa M, Hedges Joanne, Ju X, Kapellas Kostas, Leane Cathy, Haag Dandara G, Santiago Pedro Ribeiro, Macedo Davi Manzini, Roberts Rachel M, Smithers Lisa G

机构信息

Faculty of Health and Medical Sciences, Australian Research Centre for Population Oral Health, The University of Adelaide, Adelaide, South Australia, Australia

Australian Research Centre for Population Oral Health, The University of Adeliade, Adelaide, South Australia, Australia.

出版信息

BMJ Open. 2021 Feb 22;11(2):e043559. doi: 10.1136/bmjopen-2020-043559.

Abstract

PURPOSE

The South Australian Aboriginal Birth Cohort (SAABC) is a prospective, longitudinal birth cohort established to: (1) estimate Aboriginal child dental disease compared with population estimates; (2) determine the efficacy of an early childhood caries intervention in early versus late infancy; (3) examine if efficacy was sustained over time and; (4) document factors influencing social, behavioural, cognitive, anthropometric, dietary and educational attainment over time.

PARTICIPANTS

The original SAABC comprised 449 women pregnant with an Aboriginal child recruited February 2011 to May 2012. At child age 2 years, 324 (74%) participants were retained, at age 3 years, 324 (74%) participants were retained and at age 5 years, 299 (69%) participants were retained. Fieldwork for follow-up at age 7 years is underway, with funding available for follow-up at age 9 years.

FINDINGS TO DATE

At baseline, 53% of mothers were aged 14-24 years and 72% had high school or less educational attainment. At age 3 years, dental disease experience was higher among children exposed to the intervention later rather than earlier in infancy. The effect was sustained at age 5 years, but rates were still higher than general child population estimates. Experiences of racism were high among mothers, with impacts on both tooth brushing and toothache. Compared with population estimates, levels of self-efficacy and self-rated oral health of mothers at baseline were low.

FUTURE PLANS

Our data have contributed to a better understanding of the environmental, behavioural, dietary, biological and psychosocial factors contributing to Aboriginal child oral and general health, and social and emotional well-being. This is beneficial in charting the trajectory of cohort participants' health and well-being overtime, particularly in identifying antecedents of chronic diseases which are highly prevalent among Aboriginal Australians. Funding for continued follow-up of the cohort will be sought.

TRIAL REGISTRATION NUMBER

ACTRN12611000111976; Post-results.

摘要

目的

南澳大利亚原住民出生队列(SAABC)是一个前瞻性纵向出生队列,其设立目的如下:(1)与总体估计数相比,估算原住民儿童的牙科疾病;(2)确定幼儿龋齿干预措施在婴儿早期与晚期的效果;(3)研究效果是否随时间持续存在;(4)记录随时间影响社会、行为、认知、人体测量、饮食和教育成就的因素。

参与者

最初的SAABC包括2011年2月至2012年5月招募的449名怀有原住民子女的孕妇。孩子2岁时,保留了324名(74%)参与者;3岁时,保留了324名(74%)参与者;5岁时,保留了299名(69%)参与者。目前正在进行7岁随访的实地调查,并有资金用于9岁随访。

迄今的研究结果

基线时,53%的母亲年龄在14 - 24岁之间,72%的母亲受教育程度为高中及以下。在3岁时,婴儿期较晚而非较早接受干预的儿童患牙科疾病的经历更多。这种影响在5岁时仍然存在,但发病率仍高于一般儿童总体估计数。母亲中种族主义经历普遍,对刷牙和牙痛都有影响。与总体估计数相比,基线时母亲的自我效能感和自我评定的口腔健康水平较低。

未来计划

我们的数据有助于更好地理解影响原住民儿童口腔和总体健康以及社会和情感幸福的环境、行为、饮食、生物和心理社会因素。这有助于绘制队列参与者健康和幸福随时间的轨迹,特别是有助于识别在澳大利亚原住民中高度流行的慢性病的先兆。将寻求为该队列的持续随访提供资金。

试验注册号

ACTRN12611000111976;结果后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3659/7903076/475977fde82b/bmjopen-2020-043559f01.jpg

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