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通过非线性梯度脉冲实现磁共振成像中的动态范围压缩

Dynamic range compression in MRI by means of a nonlinear gradient pulse.

作者信息

Wedeen V J, Chao Y S, Ackerman J L

机构信息

Department of Radiology, Massachusetts General Hospital, Boston 02114.

出版信息

Magn Reson Med. 1988 Mar;6(3):287-95. doi: 10.1002/mrm.1910060306.

Abstract

In current magnetic resonance imaging (MRI), valuable information must often be discarded because the NMR signal has greater dynamic range than the analog-to-digital converter (ADC) hardware. Typically, a small set of high-intensity data points near the center of the spin echo is responsible for most of the MRI data dynamic range. We predict that it is possible to reduce the dynamic range of the MRI spin echo by incorporating an identical nonlinear gradient pulse into each repetition of the imaging pulse sequence, prior to data sampling. This pulse converts the phase distribution of the subject, ordinarily a linear function of image coordinates, into a nonlinear function. A nonlinear phase distribution can have a negligible impact on image magnitude and yet a profound impact on spin-echo magnitude. Given a nonlinear phase distribution, there will no longer be a single data point at which all of the protons have an identical phase (the echo center). Instead, the protons become phase coherent on a piecemeal basis, the echo peak is smoothed out, and its maximum amplitude and dynamic range are greatly diminished. Using gradient pulses of quadratic spatial variation, we estimate that maximum echo amplitude and dynamic range can be reduced in most cases by an order of magnitude.

摘要

在当前的磁共振成像(MRI)中,由于核磁共振(NMR)信号的动态范围大于模数转换器(ADC)硬件,有价值的信息常常不得不被舍弃。通常,自旋回波中心附近的一小部分高强度数据点构成了MRI数据动态范围的大部分。我们预测,在数据采样之前,通过在成像脉冲序列的每次重复中加入一个相同的非线性梯度脉冲,有可能减小MRI自旋回波的动态范围。这个脉冲将通常是图像坐标线性函数的受试者相位分布转换为非线性函数。非线性相位分布对图像幅度的影响可以忽略不计,但对自旋回波幅度却有深远影响。给定一个非线性相位分布,将不再存在所有质子具有相同相位的单个数据点(回波中心)。相反,质子会逐段地变得相位相干,回波峰值被平滑,其最大幅度和动态范围会大大减小。使用二次空间变化的梯度脉冲,我们估计在大多数情况下,最大回波幅度和动态范围可以降低一个数量级。

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