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在无烟环境中停留后支持戒烟和预防复吸:一项荟萃分析和有效行为改变技术调查。

Supporting smoking cessation and preventing relapse following a stay in a smoke-free setting: a meta-analysis and investigation of effective behaviour change techniques.

机构信息

Department of Health Sciences, University of York, Heslington, York, YO10 5DD, UK.

Centre for Behaviour Change, University College London, London, UK.

出版信息

Addiction. 2021 Nov;116(11):2978-2994. doi: 10.1111/add.15452. Epub 2021 Mar 6.

Abstract

BACKGROUND AND AIMS

Admission to a smoke-free setting presents a unique opportunity to encourage smokers to quit. However, risk of relapse post-discharge is high, and little is known about effective strategies to support smoking cessation following discharge. We aimed to identify interventions that maintain abstinence following a smoke-free stay and determine their effectiveness, as well as the probable effectiveness of behaviour change techniques (BCTs) used in these interventions.

METHODS

Systematic review and meta-analyses of studies of adult smokers aged ≥ 18 years who were temporarily or fully abstinent from smoking to comply with institutional smoke-free policies. Institutions included prison, inpatient mental health, substance misuse or acute hospital settings. A Mantel-Haenszel random-effects meta-analysis of randomized controlled trials (RCTs) was conducted using biochemically verified abstinence (7-day point prevalence or continuous abstinence). BCTs were defined as 'promising' in terms of probable effectiveness (if BCT was present in two or more long-term effective interventions) and feasibility (if BCT was also delivered in ≥ 25% of all interventions).

RESULTS

Thirty-seven studies (intervention n = 9041, control n = 6195) were included: 23 RCTs (intervention n = 6593, control n = 5801); three non-randomized trials (intervention n = 845, control n = 394) and 11 cohort studies (n = 1603). Meta-analysis of biochemically verified abstinence at longest follow-up (4 weeks-18 months) found an overall effect in favour of intervention [risk ratio (RR) = 1.27, 95% confidence interval (CI) = 1.08-1.49, I  = 42%]. Nine BCTs (including 'pharmacological support', 'goal-setting (behaviour)' and 'social support') were characterized as 'promising' in terms of probable effectiveness and feasibility.

CONCLUSIONS

A systematic review and meta-analyses indicate that behavioural and pharmacological support is effective in maintaining smoking abstinence following a stay in a smoke-free institution. Several behaviour change techniques may help to maintain smoking abstinence up to 18 months post-discharge.

摘要

背景和目的

进入无烟环境是鼓励吸烟者戒烟的独特机会。然而,出院后复发的风险很高,对于支持出院后戒烟的有效策略知之甚少。我们旨在确定维持无烟逗留期间戒烟的干预措施,并确定其有效性,以及这些干预措施中使用的行为改变技术(BCT)的可能有效性。

方法

对年龄≥18 岁的成年吸烟者进行系统评价和荟萃分析,这些吸烟者因遵守机构无烟政策而暂时或完全戒烟。机构包括监狱、住院精神卫生、药物滥用或急性医院环境。对符合条件的随机对照试验(RCT)进行 Mantel-Haenszel 随机效应荟萃分析,使用生物化学验证的戒烟(7 天点流行率或连续戒烟)。BCT 被定义为“有希望的”,即根据可能的有效性(如果 BCT 存在于两个或更多长期有效的干预措施中)和可行性(如果 BCT 也在≥25%的所有干预措施中提供)。

结果

共纳入 37 项研究(干预组 n=9041,对照组 n=6195):23 项 RCT(干预组 n=6593,对照组 n=5801);3 项非随机试验(干预组 n=845,对照组 n=394)和 11 项队列研究(n=1603)。最长随访(4 周-18 个月)时生物化学验证的戒烟的荟萃分析发现干预组总体效果有利[风险比(RR)=1.27,95%置信区间(CI)=1.08-1.49,I=42%]。有 9 种 BCT(包括“药物支持”、“目标设定(行为)”和“社会支持”)被描述为“有希望的”,这是基于可能的有效性和可行性。

结论

系统评价和荟萃分析表明,行为和药物支持在维持无烟环境逗留期间的戒烟方面是有效的。几种行为改变技术可能有助于在出院后 18 个月内保持戒烟。

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